新冠肺炎大流行期间功能训练与在线营养教育对自闭症儿童代谢状况的影响——随机临床试验

Kimia Moiniafshari, M. Gholami, Hamid Dalvand, M. Efatpanah, S. Rezayi
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摘要

缺乏身体活动和不良饮食模式被认为是ASD (ASD)中与健康相关的挑战,这似乎受到Covid-19大流行的影响。本临床试验的目的是研究功能训练和在线营养教育对ASD儿童代谢相关生物标志物的影响。80例经证实的ASD患儿(年龄=9.73±1.29,体重=49.94±2.08 kg,身高=146.08±40 cm, BMI百分位数= 64.88±2.89,FM百分比+24.71±1.48)随机分为四组:(1)功能训练组,(2)在线营养教育组,(3)训练+教育组,(4)对照组。对代谢相关生物标志物进行预测,各实验组接受干预8周。8周后进行后测。本研究的结果显示,腰宽比没有显著变化(sig=0.06)。FM (sig<0.001)、TC(sig<0.001)、TG (sig=0.006)、HDL (sig<0.001)、LDL (sig=0.001)、HOMA (sig=0.04)有显著变化。综上所述,在Covid-19大流行期间,功能训练和在线营养教育可以被认为是改善ASD儿童代谢相关生物标志物的有益干预措施。
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Evaluation of functional training along with online nutritional education on autistic children's metabolic status during Covid-19 pandemic-A randomized clinical trial
Physical inactivity and poor dietary pattern are considered as health related challenges in ASD (ASD) which seems to be affected by Covid-19 pandemic. The purpose of this clinical trial was to investigate the effect of functional training along with online nutritional education on metabolic related biomarkers in children with ASD. 80 verified children with ASD (age=9.73 ± 1.29, weight=49.94 ± 2.08 kg, stature=146.08 ± 40 cm, BMI percentile= 64.88 ± 2.89, FM percentage+24.71 ± 1.48) were randomly divided into four groups including: (1) functional training, (2) online nutritional education, 3) training+ education and 4) control group. Pre-test was taken for metabolic related biomarkers and each experimental group received their interventions for 8 weeks. Post-test was taken at the end of 8 weeks. The results from this study, did not show significant changes for WHR (sig=0.06). Significant changes was indicated for FM (sig<0.001), TC(sig<0.001), TG (sig=0.006), HDL (sig<0.001), LDL (sig=0.001), HOMA (sig=0.04). In conclusion, functional training and online nutritional education can be considered as beneficial interventions for metabolic related biomarkers improvement in children with ASD during Covid-19 pandemic.
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