首页 > 最新文献

The African journal of diabetes medicine最新文献

英文 中文
Insulin dependent diabetes and anthropometric assessment: Understanding the rationale for body composition measurement. 胰岛素依赖型糖尿病和人体测量评估:了解身体成分测量的基本原理。
Pub Date : 2022-06-01 DOI: 10.54931/2053-4787.30-6-1
Jonathan Nsamba, Elezebeth Mathews, Ronald Buyinza

The purpose of the review is to explore the interlinkages between diabetes, insulin therapy, and body composition and discuss the need for body composition assessment as part of the routine nutrition and health assessment of children living with diabetes especially in resource limited contexts with a case study of Uganda. Changes in body composition have an intractable effect of Insulin Dependent Diabetes Mellitus and its management. The association between diabetes and body composition has the potential to lead to adverse health outcomes, especially in later years of life. Health practitioners shall devise strategies to efficiently monitor the body composition of young diabetics at an early stage to revert the life threatening complications among young diabetic patients.

审查的目的是探讨糖尿病、胰岛素治疗和身体成分之间的相互联系,并讨论身体成分评估作为糖尿病儿童常规营养和健康评估的一部分的必要性,特别是在资源有限的情况下,乌干达的一个案例研究。胰岛素依赖型糖尿病及其治疗中,身体成分的改变是一个棘手的问题。糖尿病和身体成分之间的联系有可能导致不良的健康结果,特别是在晚年。医护人员应制定策略,在早期阶段有效地监测青年糖尿病患者的身体成分,以恢复青年糖尿病患者危及生命的并发症。
{"title":"Insulin dependent diabetes and anthropometric assessment: Understanding the rationale for body composition measurement.","authors":"Jonathan Nsamba,&nbsp;Elezebeth Mathews,&nbsp;Ronald Buyinza","doi":"10.54931/2053-4787.30-6-1","DOIUrl":"https://doi.org/10.54931/2053-4787.30-6-1","url":null,"abstract":"<p><p>The purpose of the review is to explore the interlinkages between diabetes, insulin therapy, and body composition and discuss the need for body composition assessment as part of the routine nutrition and health assessment of children living with diabetes especially in resource limited contexts with a case study of Uganda. Changes in body composition have an intractable effect of Insulin Dependent Diabetes Mellitus and its management. The association between diabetes and body composition has the potential to lead to adverse health outcomes, especially in later years of life. Health practitioners shall devise strategies to efficiently monitor the body composition of young diabetics at an early stage to revert the life threatening complications among young diabetic patients.</p>","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614593/pdf/EMS175052.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9588422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-silico works on the control of blood glucose level for different Type 1 Diabetes Mellitus Subjects using improved Hovorka equations 利用改进的Hovorka方程控制不同1型糖尿病受试者的血糖水平
Pub Date : 2022-06-01 DOI: 10.54931/30-6-2
Ayub Md Som, Nam Sohadi, MF Johari, Sa Ali, Nsm Nor, M. Ahmad
Background: One of the most common types of diabetes is Type 1 Diabetes Mellitus (T1DM) which causes high or low blood glucose levels (BGL) in a patient’s body. T1DM patients need to maintain their BGL in a safe glycemic range which is between 4.0 mmol/L to 7 mmol/L. Thus, it is high time to find the optimum insulin infusion rate into the patient’s body in achieving prolonged normoglycemic range. Methods: Previous workers had focused on employing the improved Hovorka equations via in-silico study using one T1DM patient’s data; however, in-silico works employing more actual patients’ data are yet to be explored. Hence, this study attempts to apply the improved Hovorka equations on three different T1DM subjects so as to simulate their BGL profiles based on daily stipulated meal disturbances, individual body weights and age group. Results: Results showed that the optimum insulin infusion rates required to regulate the BGL within safe glycemic range were at 0.1 U/min, 0.05 U/min and 0.0167 U/min for the case of patients 1, 2 and 3, respectively; provided that different amounts of meal intake (DG) were observed by each patient during breakfast, lunch and dinner times. Conclusion: In conclusion, this study had proven that the improved Hovorka equations can be used to simulate the meal disturbance effect on BGL for more T1DM patients. Keywords Blood glucose level; Closed-loop control system; Hovorka model; Meal disturbance; Type 1 diabetes mellitus
背景:1型糖尿病(T1DM)是最常见的糖尿病类型之一,它引起患者体内的高血糖或低血糖水平(BGL)。T1DM患者需要将BGL维持在4.0 ~ 7mmol /L的安全血糖范围内。因此,在延长血糖正常范围的过程中,寻找最佳的胰岛素输注速率是当务之急。方法:以往的工作主要是利用1例T1DM患者的数据,通过计算机研究,采用改进的Hovorka方程;然而,使用更多实际患者数据的计算机工作还有待探索。因此,本研究尝试将改进的Hovorka方程应用于3个不同的T1DM受试者,基于每日规定膳食干扰、个体体重和年龄组模拟其BGL分布。结果:患者1、2、3的最佳胰岛素输注速率分别为0.1 U/min、0.05 U/min和0.0167 U/min;前提是每位患者在早餐、午餐和晚餐时间的膳食摄入量(DG)不同。结论:本研究证明改进的Hovorka方程可用于模拟更多T1DM患者饮食干扰对BGL的影响。血糖水平;闭环控制系统;Hovorka模型;餐干扰;1型糖尿病
{"title":"In-silico works on the control of blood glucose level for different Type 1 Diabetes Mellitus Subjects using improved Hovorka equations","authors":"Ayub Md Som, Nam Sohadi, MF Johari, Sa Ali, Nsm Nor, M. Ahmad","doi":"10.54931/30-6-2","DOIUrl":"https://doi.org/10.54931/30-6-2","url":null,"abstract":"Background: One of the most common types of diabetes is Type 1 Diabetes Mellitus (T1DM) which causes high or low blood glucose levels (BGL) in a patient’s body. T1DM patients need to maintain their BGL in a safe glycemic range which is between 4.0 mmol/L to 7 mmol/L. Thus, it is high time to find the optimum insulin infusion rate into the patient’s body in achieving prolonged normoglycemic range. Methods: Previous workers had focused on employing the improved Hovorka equations via in-silico study using one T1DM patient’s data; however, in-silico works employing more actual patients’ data are yet to be explored. Hence, this study attempts to apply the improved Hovorka equations on three different T1DM subjects so as to simulate their BGL profiles based on daily stipulated meal disturbances, individual body weights and age group. Results: Results showed that the optimum insulin infusion rates required to regulate the BGL within safe glycemic range were at 0.1 U/min, 0.05 U/min and 0.0167 U/min for the case of patients 1, 2 and 3, respectively; provided that different amounts of meal intake (DG) were observed by each patient during breakfast, lunch and dinner times. Conclusion: In conclusion, this study had proven that the improved Hovorka equations can be used to simulate the meal disturbance effect on BGL for more T1DM patients. Keywords Blood glucose level; Closed-loop control system; Hovorka model; Meal disturbance; Type 1 diabetes mellitus","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"134 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77395435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insulin dependent diabetes and anthropometric assessment: Understanding the rationale for body composition measurement. 胰岛素依赖型糖尿病和人体测量评估:了解身体成分测量的基本原理。
Pub Date : 2022-06-01 DOI: 10.54931/2053-4787.30-6
Jonathan Nsamba, E. Mathews, Ronald Buyinza
The purpose of the review is to explore the interlinkages between diabetes, insulin therapy, and body composition and discuss the need for body composition assessment as part of the routine nutrition and health assessment of children living with diabetes especially in resource limited contexts with a case study of Uganda. Changes in body composition have an intractable effect of Insulin Dependent Diabetes Mellitus and its management. The association between diabetes and body composition has the potential to lead to adverse health outcomes, especially in later years of life. Health practitioners shall devise strategies to efficiently monitor the body composition of young diabetics at an early stage to revert the life threatening complications among young diabetic patients.
审查的目的是探讨糖尿病、胰岛素治疗和身体成分之间的相互联系,并讨论身体成分评估作为糖尿病儿童常规营养和健康评估的一部分的必要性,特别是在资源有限的情况下,乌干达的一个案例研究。胰岛素依赖型糖尿病及其治疗中,身体成分的改变是一个棘手的问题。糖尿病和身体成分之间的联系有可能导致不良的健康结果,特别是在晚年。医护人员应制定策略,在早期阶段有效地监测青年糖尿病患者的身体成分,以恢复青年糖尿病患者危及生命的并发症。
{"title":"Insulin dependent diabetes and anthropometric assessment: Understanding the rationale for body composition measurement.","authors":"Jonathan Nsamba, E. Mathews, Ronald Buyinza","doi":"10.54931/2053-4787.30-6","DOIUrl":"https://doi.org/10.54931/2053-4787.30-6","url":null,"abstract":"The purpose of the review is to explore the interlinkages between diabetes, insulin therapy, and body composition and discuss the need for body composition assessment as part of the routine nutrition and health assessment of children living with diabetes especially in resource limited contexts with a case study of Uganda. Changes in body composition have an intractable effect of Insulin Dependent Diabetes Mellitus and its management. The association between diabetes and body composition has the potential to lead to adverse health outcomes, especially in later years of life. Health practitioners shall devise strategies to efficiently monitor the body composition of young diabetics at an early stage to revert the life threatening complications among young diabetic patients.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75660510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A decade anti-diabetic potential of murraya koenigii (curry leaf): A narrative review 咖喱叶的十年抗糖尿病潜力:述评
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-3-2
Arefeh Tabashiri, Mohammad Sadegh Qadirifard, A. Ghaderi, Maryam Rahmannia, Amir Mohammad Sharafi, Shamim Kiani, Farhad Nikzad, A. Ansari, Faezeh Soveyzi, N. Deravi
Diabetes is a widely known disease, which afflicts millions of people annually and is considered one of the leading culprits of mortality and morbidity worldwide. Researchers are making an enormous effort to propose more efficient remedies for the better amelioration of the disease. On the other hand, the public interest in the consumption of herbal medicine for therapeutic purposes is rocketing and the use of these drugs is becoming ubiquitous. Murraya koenigii MK is a tropical tree, originally found in the Indian subcontinent, which is an indispensable piece of the Indian diet and has multipotent medicinal capa -bilities. The variety of its leaves’ hypoglycemic characteristics has been investigated via human, animal, and in vitro studies. This review intends to elaborate on the latest knowledge about the anti-diabetic and hypoglycemic effects of MK in the hope of easing the further application of MK in the alleviation of the diabetes signs and symptoms.
糖尿病是一种众所周知的疾病,每年折磨数百万人,被认为是世界范围内死亡率和发病率的主要罪魁祸首之一。研究人员正在作出巨大的努力,提出更有效的补救措施,以更好地改善这种疾病。另一方面,公众对以治疗为目的的草药消费的兴趣正在飙升,这些药物的使用正变得无处不在。Murraya koenigii MK是一种热带树木,最初发现于印度次大陆,是印度饮食中不可或缺的一部分,具有多种药用能力。通过人体、动物和体外研究,研究了其叶片的各种降糖特性。现就其抗糖尿病降糖作用的最新研究进展作一综述,以期对其在缓解糖尿病症状和体征方面的进一步应用有所裨益。
{"title":"A decade anti-diabetic potential of murraya koenigii (curry leaf): A narrative review","authors":"Arefeh Tabashiri, Mohammad Sadegh Qadirifard, A. Ghaderi, Maryam Rahmannia, Amir Mohammad Sharafi, Shamim Kiani, Farhad Nikzad, A. Ansari, Faezeh Soveyzi, N. Deravi","doi":"10.54931/2053-4787.30-3-2","DOIUrl":"https://doi.org/10.54931/2053-4787.30-3-2","url":null,"abstract":"Diabetes is a widely known disease, which afflicts millions of people annually and is considered one of the leading culprits of mortality and morbidity worldwide. Researchers are making an enormous effort to propose more efficient remedies for the better amelioration of the disease. On the other hand, the public interest in the consumption of herbal medicine for therapeutic purposes is rocketing and the use of these drugs is becoming ubiquitous. Murraya koenigii MK is a tropical tree, originally found in the Indian subcontinent, which is an indispensable piece of the Indian diet and has multipotent medicinal capa -bilities. The variety of its leaves’ hypoglycemic characteristics has been investigated via human, animal, and in vitro studies. This review intends to elaborate on the latest knowledge about the anti-diabetic and hypoglycemic effects of MK in the hope of easing the further application of MK in the alleviation of the diabetes signs and symptoms.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75220108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric endocrinology and diabetes mapping and services in Nigeria: A decade after 尼日利亚儿科内分泌学和糖尿病制图与服务:十年后
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-2-1
Yarhere Iroro E, Jaja Tamunopriye
Purpose: Paediatric endocrinology services are relatively new in Africa and Nigeria and the services and resources for the children with diabetes and other endocrine disorders are poorly de-veloped. We aimed to survey pediatric endocrinology services in Nigeria using an online survey tool. Methods: We surveyed the paediatric endocrinologists practicing in public tertiary institutions in Nigeria using an instrument designed to evaluate the availability of manpower, infrastructures, specific medications, and collaborations with other endo crinologists. Results: Fifteen of the 37 practicing paediatric endocrinologists responded, giving a response rate of h a response rate of 40.5%. The mean practice years was 9.3 (range 7-12), and many had skills in managing children with diabetes, thyroid and growth abnormalities. All centres had facilities for ultrasound scan and simple diagnostic techniques but few centres had access to iodine uptake studies, antibody testing and special hormones. While most centres could outsource special tests, patients could rarely afford the services. There were 297 children on manage ment for TIDM and over 90% of these were on pre-mix insulin. Conclusion: The dearth in human and infrastructural capacity in paediatric endocrinology services should be improved on and this will alleviate the burden of diabetes and endocrine disorders in Nigerian children. means the test can be outsourced in a peripheral laboratory not attached to the home center of the paediatric endocrinologist.
目的:儿科内分泌服务在非洲和尼日利亚相对较新,针对糖尿病和其他内分泌疾病儿童的服务和资源不发达。我们旨在使用在线调查工具调查尼日利亚的儿科内分泌学服务。方法:我们调查了在尼日利亚公立高等院校执业的儿科内分泌学家,使用了一种旨在评估人力、基础设施、特定药物的可用性以及与其他内分泌学家合作情况的工具。结果:37名儿科内分泌科执业医师中有15名有应答,应答率为40.5%。平均实习年限为9.3年(范围7-12年),其中许多人具备管理患有糖尿病、甲状腺和生长异常的儿童的技能。所有中心都有超声波扫描和简单诊断技术的设施,但很少有中心有碘摄取研究、抗体测试和特殊激素。虽然大多数中心可以外包特殊检测,但病人很少负担得起这种服务。297名儿童接受了TIDM治疗,其中90%以上的儿童接受了预混合胰岛素治疗。结论:应改善儿科内分泌服务人员和基础设施能力的缺乏,这将减轻尼日利亚儿童糖尿病和内分泌疾病的负担。意味着测试可以外包到外围实验室,不附属于儿科内分泌学家的家庭中心。
{"title":"Paediatric endocrinology and diabetes mapping and services in Nigeria: A decade after","authors":"Yarhere Iroro E, Jaja Tamunopriye","doi":"10.54931/2053-4787.30-2-1","DOIUrl":"https://doi.org/10.54931/2053-4787.30-2-1","url":null,"abstract":"Purpose: Paediatric endocrinology services are relatively new in Africa and Nigeria and the services and resources for the children with diabetes and other endocrine disorders are poorly de-veloped. We aimed to survey pediatric endocrinology services in Nigeria using an online survey tool. Methods: We surveyed the paediatric endocrinologists practicing in public tertiary institutions in Nigeria using an instrument designed to evaluate the availability of manpower, infrastructures, specific medications, and collaborations with other endo crinologists. Results: Fifteen of the 37 practicing paediatric endocrinologists responded, giving a response rate of h a response rate of 40.5%. The mean practice years was 9.3 (range 7-12), and many had skills in managing children with diabetes, thyroid and growth abnormalities. All centres had facilities for ultrasound scan and simple diagnostic techniques but few centres had access to iodine uptake studies, antibody testing and special hormones. While most centres could outsource special tests, patients could rarely afford the services. There were 297 children on manage ment for TIDM and over 90% of these were on pre-mix insulin. Conclusion: The dearth in human and infrastructural capacity in paediatric endocrinology services should be improved on and this will alleviate the burden of diabetes and endocrine disorders in Nigerian children. means the test can be outsourced in a peripheral laboratory not attached to the home center of the paediatric endocrinologist.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90383510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socio-Demographic Profile, Asymptomatic Malaria Parasitaemia and Glycemic Control among Midled-Aged and Elderly Type 2 Diabetes Mellitus Patients in Rural Southwestern Nigeria: A Cross Sectional Study 尼日利亚西南部农村中老年2型糖尿病患者的社会人口特征、无症状疟疾、寄生虫血症和血糖控制:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-3-1
A. Ibrahim, G. Ajani, K. Adewoye, T. Olanrewaju, Eniola Ayoyemi Afolabi-Obe, A. Ibikunle
The main therapeutic goal for all type 2 diabetes mellitus (T2DM) patients is to maintain good control so as to prevent the risk of complications associated with poor control. This study determined the prevalence of poor control and its association with socio-demographics and malaria parasitaemia among middle aged and elderly T2DM patients at a tertiary hospital in rural Southwestern Nigeria. We conducted a retrospective observational study on 250 T2DM using semi-structured interviewer administered questionnaire. Venous blood samples were collected and processed for glycated hemoglobin sugar estimation and malaria parasite detection by microscopy. Data were analyzed using SPSS version 20.0. Multivariate logistic regression identi-fied the association of socio-demographics and asymptomatic malaria parasitaemia with poor control. The prevalence of poor glycemic control was 31.6% (95%CI: 34.4%-45.8%). Old age, (AOR=4.868; 95% CI: 1.258-24.574), female genders (AOR=7.100; 95% CI: 1.875-34.655), no formal education (AOR=3.447; 95% CI: 1.098-21.478), presence of malaria parasitaemia (AOR=48.423; 95% CI: 4.987-411.366), and higher parasite density (AOR=7.102; 95% CI: 1.785-15.002), were significantly associated with poor control. Health facilities should integrate screening of malaria parasitaemia into the management of T2DM patients while also exploring other barriers of poor control.
所有2型糖尿病(T2DM)患者的主要治疗目标是保持良好的控制,以防止因控制不良而发生并发症的风险。本研究确定了尼日利亚西南部农村一家三级医院中老年2型糖尿病患者控制不良的患病率及其与社会人口统计学和疟疾寄生虫病的关系。我们采用半结构化访谈问卷对250例T2DM患者进行回顾性观察研究。采集静脉血,镜检糖化血红蛋白和疟原虫。数据分析采用SPSS 20.0版本。多变量logistic回归确定了社会人口统计学与控制不良的无症状疟疾寄生虫病的关联。血糖控制不良的患病率为31.6% (95%CI: 34.4% ~ 45.8%)。老年,(AOR=4.868;95% CI: 1.258-24.574),女性(AOR=7.100;95% CI: 1.875-34.655),无正规教育(AOR=3.447;95% CI: 1.098-21.478),存在疟疾寄生虫血症(AOR=48.423;95% CI: 4.987-411.366),较高的寄生虫密度(AOR=7.102;95% CI: 1.785-15.002),与控制不良显著相关。卫生机构应将疟疾寄生虫病筛查纳入2型糖尿病患者的管理,同时探索控制不良的其他障碍。
{"title":"Socio-Demographic Profile, Asymptomatic Malaria Parasitaemia and Glycemic Control among Midled-Aged and Elderly Type 2 Diabetes Mellitus Patients in Rural Southwestern Nigeria: A Cross Sectional Study","authors":"A. Ibrahim, G. Ajani, K. Adewoye, T. Olanrewaju, Eniola Ayoyemi Afolabi-Obe, A. Ibikunle","doi":"10.54931/2053-4787.30-3-1","DOIUrl":"https://doi.org/10.54931/2053-4787.30-3-1","url":null,"abstract":"The main therapeutic goal for all type 2 diabetes mellitus (T2DM) patients is to maintain good control so as to prevent the risk of complications associated with poor control. This study determined the prevalence of poor control and its association with socio-demographics and malaria parasitaemia among middle aged and elderly T2DM patients at a tertiary hospital in rural Southwestern Nigeria. We conducted a retrospective observational study on 250 T2DM using semi-structured interviewer administered questionnaire. Venous blood samples were collected and processed for glycated hemoglobin sugar estimation and malaria parasite detection by microscopy. Data were analyzed using SPSS version 20.0. Multivariate logistic regression identi-fied the association of socio-demographics and asymptomatic malaria parasitaemia with poor control. The prevalence of poor glycemic control was 31.6% (95%CI: 34.4%-45.8%). Old age, (AOR=4.868; 95% CI: 1.258-24.574), female genders (AOR=7.100; 95% CI: 1.875-34.655), no formal education (AOR=3.447; 95% CI: 1.098-21.478), presence of malaria parasitaemia (AOR=48.423; 95% CI: 4.987-411.366), and higher parasite density (AOR=7.102; 95% CI: 1.785-15.002), were significantly associated with poor control. Health facilities should integrate screening of malaria parasitaemia into the management of T2DM patients while also exploring other barriers of poor control.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80107484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Trajectories of lived experiences of people living with Diabetes Mellitus in Africa: An evidence mapping of conceptual framework 非洲糖尿病患者的生活经历轨迹:概念框架的证据映射
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-1-4
D. Klu, R. Alhassan, M. Dalaba, P. Doegah
Introduction: Diabetes Mellitus remains a major public health problem in Africa in the last two decades. A new conceptual framework for studying and understanding trajectories of experiences of people with diabetes mellitus in Africa is presented. Objective: The paper examines all known factors influencing the trajectories of lived experiences of persons with diabetes and how these factors interact with each other at micro and macro levels. Methods: A systematic mapping of peer reviewed literature (n=61) conducted in Africa and published between 01/01/1990 and 31/12/2020 was utilised. Results: Using a conceptual framework, we synthesised the factors influencing trajectories of lived experiences of diabetes in Africa, grouped into six domains: diabetes risk factors, socio-demographic characteristics, individual level experiences, household/family level experiences, community/society level experiences and national level experiences. Conclusion: This framework can be used to test hypotheses about facilitators and barriers to health care-seeking behaviour. As well as understand how trajectories of lived experience of diabetes might be influenced by policy or practice. Research based on understanding of trajectories is expected to improve diabetes patient’s experiences and outcome in diabetes management and care in Africa.
在过去的二十年中,糖尿病仍然是非洲的一个主要公共卫生问题。为研究和理解非洲糖尿病患者的经历轨迹提出了一个新的概念框架。目的:探讨影响糖尿病患者生活经历轨迹的所有已知因素,以及这些因素在微观和宏观层面上如何相互作用。方法:对1990年1月1日至2020年12月31日期间在非洲发表的同行评议文献(n=61)进行系统制图。结果:使用概念框架,我们综合了影响非洲糖尿病生活经历轨迹的因素,将其分为六个领域:糖尿病风险因素、社会人口特征、个人层面经验、家庭/家庭层面经验、社区/社会层面经验和国家层面经验。结论:该框架可用于检验关于就医行为的促进因素和障碍的假设。以及了解糖尿病生活经历的轨迹如何受到政策或实践的影响。基于对糖尿病发展轨迹的了解的研究有望改善非洲糖尿病患者在糖尿病管理和护理方面的经验和结果。
{"title":"Trajectories of lived experiences of people living with Diabetes Mellitus in Africa: An evidence mapping of conceptual framework","authors":"D. Klu, R. Alhassan, M. Dalaba, P. Doegah","doi":"10.54931/2053-4787.30-1-4","DOIUrl":"https://doi.org/10.54931/2053-4787.30-1-4","url":null,"abstract":"Introduction: Diabetes Mellitus remains a major public health problem in Africa in the last two decades. A new conceptual framework for studying and understanding trajectories of experiences of people with diabetes mellitus in Africa is presented. Objective: The paper examines all known factors influencing the trajectories of lived experiences of persons with diabetes and how these factors interact with each other at micro and macro levels. Methods: A systematic mapping of peer reviewed literature (n=61) conducted in Africa and published between 01/01/1990 and 31/12/2020 was utilised. Results: Using a conceptual framework, we synthesised the factors influencing trajectories of lived experiences of diabetes in Africa, grouped into six domains: diabetes risk factors, socio-demographic characteristics, individual level experiences, household/family level experiences, community/society level experiences and national level experiences. Conclusion: This framework can be used to test hypotheses about facilitators and barriers to health care-seeking behaviour. As well as understand how trajectories of lived experience of diabetes might be influenced by policy or practice. Research based on understanding of trajectories is expected to improve diabetes patient’s experiences and outcome in diabetes management and care in Africa.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"90 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72424819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of functional training along with online nutritional education on autistic children's metabolic status during Covid-19 pandemic-A randomized clinical trial 新冠肺炎大流行期间功能训练与在线营养教育对自闭症儿童代谢状况的影响——随机临床试验
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-1-3
Kimia Moiniafshari, M. Gholami, Hamid Dalvand, M. Efatpanah, S. Rezayi
Physical inactivity and poor dietary pattern are considered as health related challenges in ASD (ASD) which seems to be affected by Covid-19 pandemic. The purpose of this clinical trial was to investigate the effect of functional training along with online nutritional education on metabolic related biomarkers in children with ASD. 80 verified children with ASD (age=9.73 ± 1.29, weight=49.94 ± 2.08 kg, stature=146.08 ± 40 cm, BMI percentile= 64.88 ± 2.89, FM percentage+24.71 ± 1.48) were randomly divided into four groups including: (1) functional training, (2) online nutritional education, 3) training+ education and 4) control group. Pre-test was taken for metabolic related biomarkers and each experimental group received their interventions for 8 weeks. Post-test was taken at the end of 8 weeks. The results from this study, did not show significant changes for WHR (sig=0.06). Significant changes was indicated for FM (sig<0.001), TC(sig<0.001), TG (sig=0.006), HDL (sig<0.001), LDL (sig=0.001), HOMA (sig=0.04). In conclusion, functional training and online nutritional education can be considered as beneficial interventions for metabolic related biomarkers improvement in children with ASD during Covid-19 pandemic.
缺乏身体活动和不良饮食模式被认为是ASD (ASD)中与健康相关的挑战,这似乎受到Covid-19大流行的影响。本临床试验的目的是研究功能训练和在线营养教育对ASD儿童代谢相关生物标志物的影响。80例经证实的ASD患儿(年龄=9.73±1.29,体重=49.94±2.08 kg,身高=146.08±40 cm, BMI百分位数= 64.88±2.89,FM百分比+24.71±1.48)随机分为四组:(1)功能训练组,(2)在线营养教育组,(3)训练+教育组,(4)对照组。对代谢相关生物标志物进行预测,各实验组接受干预8周。8周后进行后测。本研究的结果显示,腰宽比没有显著变化(sig=0.06)。FM (sig<0.001)、TC(sig<0.001)、TG (sig=0.006)、HDL (sig<0.001)、LDL (sig=0.001)、HOMA (sig=0.04)有显著变化。综上所述,在Covid-19大流行期间,功能训练和在线营养教育可以被认为是改善ASD儿童代谢相关生物标志物的有益干预措施。
{"title":"Evaluation of functional training along with online nutritional education on autistic children's metabolic status during Covid-19 pandemic-A randomized clinical trial","authors":"Kimia Moiniafshari, M. Gholami, Hamid Dalvand, M. Efatpanah, S. Rezayi","doi":"10.54931/2053-4787.30-1-3","DOIUrl":"https://doi.org/10.54931/2053-4787.30-1-3","url":null,"abstract":"Physical inactivity and poor dietary pattern are considered as health related challenges in ASD (ASD) which seems to be affected by Covid-19 pandemic. The purpose of this clinical trial was to investigate the effect of functional training along with online nutritional education on metabolic related biomarkers in children with ASD. 80 verified children with ASD (age=9.73 ± 1.29, weight=49.94 ± 2.08 kg, stature=146.08 ± 40 cm, BMI percentile= 64.88 ± 2.89, FM percentage+24.71 ± 1.48) were randomly divided into four groups including: (1) functional training, (2) online nutritional education, 3) training+ education and 4) control group. Pre-test was taken for metabolic related biomarkers and each experimental group received their interventions for 8 weeks. Post-test was taken at the end of 8 weeks. The results from this study, did not show significant changes for WHR (sig=0.06). Significant changes was indicated for FM (sig<0.001), TC(sig<0.001), TG (sig=0.006), HDL (sig<0.001), LDL (sig=0.001), HOMA (sig=0.04). In conclusion, functional training and online nutritional education can be considered as beneficial interventions for metabolic related biomarkers improvement in children with ASD during Covid-19 pandemic.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91131174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of nonlinear resistance training on serum myostatin and insulin resistance in women with breast cancer 非线性阻力训练对乳腺癌患者血清肌生长抑制素和胰岛素抵抗的影响
Pub Date : 2022-01-01 DOI: 10.54931/2053-4787.30-1-5
Sh Shahrokhian, A. Habibi, Saeed Shakerian
{"title":"The effect of nonlinear resistance training on serum myostatin and insulin resistance in women with breast cancer","authors":"Sh Shahrokhian, A. Habibi, Saeed Shakerian","doi":"10.54931/2053-4787.30-1-5","DOIUrl":"https://doi.org/10.54931/2053-4787.30-1-5","url":null,"abstract":"","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84780473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effectiveness of digital health interventions for diabetes: systematic review of systematic reviews 糖尿病数字健康干预措施的有效性:系统综述的系统综述
Pub Date : 2021-07-15 DOI: 10.21203/RS.3.RS-722330/V1
Bonkana Maiga, C. Bagayoko, M. A. Ahmed, A. Anne, M. Gagnon, Sidibé Assa Traore, J. Landrier, A. Geissbuhler
BackgroundThe use of digital health technologies to tackle diabetes has been particularly flourishing in recent years. Previous studies have shown to varying degrees that these technologies can have an impact on diabetes prevention and management.ObjectiveThe aim of this review is to summarize the best evidence regarding the effectiveness of digital health interventions to improve one or more diabetes indicators.MethodsWe included all types of interventions aimed at evaluating the effect of digital health on diabetes. We considered at all types of digital interventions (mobile health, teleconsultations, tele-expertise, electronic health records, decision support systems, e-learning, etc.). We included systematic reviews published in English or French over the last 29 years, from January 1991 to December 2019, that met the inclusion criteria. Two reviewers independently reviewed the titles and abstracts of the studies to assess their eligibility, and extracted relevant information according to a predetermined grid. Any disagreement was resolved by discussion and consensus between the two reviewers, or involved a third author as referee.Results In total in our review of journals, we included 10 reviews. The outcomes of interest were clinical indicators of diabetes that could be influenced by digital interventions. These outcomes had to be objectively measurable indicators related to diabetes surveillance and management that are generally accepted by diabetes experts. Six of the ten reviews showed moderate to large significant reductions in glycated hemoglobin (HBA1c) levels compared to controls. Most reviews reported overall positive results and found that digital health interventions improved health care utilization, behaviours, attitudes, knowledge and skills.ConclusionBased on a large corpus of scientific evidence on digital health interventions, this overview could help identify the most effective interventions to improve diabetes indicators.
近年来,利用数字卫生技术解决糖尿病问题的情况尤为普遍。以前的研究已经在不同程度上表明,这些技术可以对糖尿病的预防和管理产生影响。目的本综述的目的是总结关于数字健康干预措施改善一项或多项糖尿病指标有效性的最佳证据。方法我们纳入了所有类型的干预措施,旨在评估数字健康对糖尿病的影响。我们考虑了所有类型的数字干预(移动医疗、远程咨询、远程专家、电子健康记录、决策支持系统、电子学习等)。我们纳入了从1991年1月至2019年12月的过去29年中以英语或法语发表的符合纳入标准的系统评价。两名审稿人独立审查研究的标题和摘要,以评估其资格,并根据预定的网格提取相关信息。任何分歧由两位审稿人讨论并达成共识,或由第三作者作为审稿人。结果在我们的期刊综述中,我们总共纳入了10篇综述。我们感兴趣的结果是糖尿病的临床指标,这些指标可能受到数字干预的影响。这些结果必须是被糖尿病专家普遍接受的与糖尿病监测和管理相关的客观可测量的指标。10篇综述中有6篇显示,与对照组相比,糖化血红蛋白(HBA1c)水平有中度到大幅度的显著降低。大多数审查报告了总体上的积极结果,并发现数字卫生干预措施改善了卫生保健的利用、行为、态度、知识和技能。基于大量关于数字健康干预的科学证据,本综述有助于确定改善糖尿病指标的最有效干预措施。
{"title":"Effectiveness of digital health interventions for diabetes: systematic review of systematic reviews","authors":"Bonkana Maiga, C. Bagayoko, M. A. Ahmed, A. Anne, M. Gagnon, Sidibé Assa Traore, J. Landrier, A. Geissbuhler","doi":"10.21203/RS.3.RS-722330/V1","DOIUrl":"https://doi.org/10.21203/RS.3.RS-722330/V1","url":null,"abstract":"\u0000 Background\u0000\u0000The use of digital health technologies to tackle diabetes has been particularly flourishing in recent years. Previous studies have shown to varying degrees that these technologies can have an impact on diabetes prevention and management.\u0000Objective\u0000\u0000The aim of this review is to summarize the best evidence regarding the effectiveness of digital health interventions to improve one or more diabetes indicators.\u0000Methods\u0000\u0000We included all types of interventions aimed at evaluating the effect of digital health on diabetes. We considered at all types of digital interventions (mobile health, teleconsultations, tele-expertise, electronic health records, decision support systems, e-learning, etc.). We included systematic reviews published in English or French over the last 29 years, from January 1991 to December 2019, that met the inclusion criteria. Two reviewers independently reviewed the titles and abstracts of the studies to assess their eligibility, and extracted relevant information according to a predetermined grid. Any disagreement was resolved by discussion and consensus between the two reviewers, or involved a third author as referee.\u0000Results\u0000\u0000 In total in our review of journals, we included 10 reviews. The outcomes of interest were clinical indicators of diabetes that could be influenced by digital interventions. These outcomes had to be objectively measurable indicators related to diabetes surveillance and management that are generally accepted by diabetes experts. Six of the ten reviews showed moderate to large significant reductions in glycated hemoglobin (HBA1c) levels compared to controls. Most reviews reported overall positive results and found that digital health interventions improved health care utilization, behaviours, attitudes, knowledge and skills.\u0000Conclusion\u0000\u0000Based on a large corpus of scientific evidence on digital health interventions, this overview could help identify the most effective interventions to improve diabetes indicators.","PeriodicalId":74927,"journal":{"name":"The African journal of diabetes medicine","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89771406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
The African journal of diabetes medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1