严重急性呼吸综合征冠状病毒引起的新生儿多系统炎症综合征2:一个新兴实体

Ashwini Nagda, V. Sawant, K. Rajput, S. Malik, Vinaya A. Singh, S. Kondekar
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引用次数: 1

摘要

2020年3月,严重急性呼吸综合征冠状病毒被宣布为大流行。受该病毒影响的成年人多于儿童,儿童的疾病严重程度较轻。我们报告了一例在生命第3、6和15天检测出2019冠状病毒感染阳性的新生儿。婴儿有发烧、呼吸窘迫和休克。实验室检查显示炎症标志物升高,D二聚体升高提示凝血功能障碍,二维超声心动图显示冠状动脉扩张,N端脑利钠肽前体升高。新生儿通过良好的支持护理、肺保护性通气策略、早期静脉注射免疫球蛋白、皮质类固醇和瑞德西韦成功治疗。
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Multisystem inflammatory syndrome in neonates due to severe acute respiratory syndrome coronavirus 2: An emerging entity
Severe acute respiratory syndrome coronavirus 2 was declared as a pandemic in March 2020. The virus has affected more adults than children, with disease severity being lesser in children. We present a case of a neonate who tested positive for coronavirus disease 2019 infection on day of life 3, 6, and 15. The baby had fever, respiratory distress, and shock. Laboratory investigations showed raised inflammatory markers, raised D dimer suggesting coagulopathy, coronary dilatation on 2D echocardiogram, and raised N terminal pro-brain natriuretic peptide. The neonate was successfully treated with good supportive care, lung-protective ventilatory strategies, early intravenous immunoglobulin administration, corticosteroids, and remdesivir.
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