专肠内营养(NEE)治疗被诊断为克罗恩病的小儿患者

Natalia Egea, Javier Martín de Carpi, Alejandra Gutiérrez Sánchez, Natalia Catalán, Vicente Varea Calderón
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摘要

一名男性,14岁11个月大,因怀疑炎症性肠病入院。他有贫血,两个月来反复发作的口疮,偶尔腹泻和体重减轻。患者既往无家族病史或个人病史。人体测量和附加测试:患者初始体重56.9 Kg,身高177 cm, BMI为18.1。在分析中,观察到轻度贫血(血红蛋白:10.7 mg/dl),缺铁(铁13 μg/dl)和炎症标志物增加(ESR 37 mm, CRP 48.2 mg/dl)。量热法:11.2%脂肪,6.4 kg脂肪质量,50.5 kg瘦肉质量。静息代谢率(千卡/天)密度测定:腰椎L2-L4骨密度正常。纤维结肠镜检查和回肠镜检查伴活检改变。小肠检查正常。在进行额外的检查后,患者被诊断患有克罗恩病。治疗:开始时给予硫唑嘌呤150 mg/dl (2.6 mg/kg),同时给予独家肠内营养:模块IBD容量/天:2800 ml, 3360 kcal/天。临床进展:从一开始,患者对药物和独家肠内营养耐受良好。在用Modulen IBD®治疗5周后,活动的爆发得到缓解(在短时间内,分析参数和营养状况有了显著改善),因此,在6周后,他的年龄开始正常饮食。体重减轻的恢复。他现在的体重保持在62.2公斤(6周内增加了5.3公斤)。
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Tratamiento con nutrición enteral exclusiva (NEE) en paciente pediátrico diagnosticado de enfermedad de Crohn

A male, 14 years and 11 month-old patient who is admitted into hospital for suspected inflammatory bowel disease. He has anaemia, recurrent aphthqe of two months’ evolution, occasional diarrhoea and weight loss. The patient has no previous family or personal history of interest of the current process. Anthropometry and additional tests: the patient has an initial weight of 56.9 Kg, a height of 177 cm and a BMI of 18.1. In the analysis, a discreet anaemia is observed (Hb: 10.7 mg/dl), iron deficiency (Fe 13 μg/dl) and an increase in the inflammatory markers (ESR 37 mm, CRP 48.2 mg/dl). Calorimetry: 11.2% fat, 6.4 kg fat mass, 50.5 kg lean mass. Resting metabolic rate (kcal/day) 1373. Densitometry: The bone density of the lumbar spine L2–L4 is considered normal. Fibrocolonoscopy and ileoscopy with biopsy with alterations. The small bowel follow-through was normal. After the additional tests are carried out, the patient is diagnosed with Crohn's disease. Treatment: is begun with azathioprine 150 mg/dl (2.6 mg/kg) in parallel with exclusive enteral nutrition: Modulen IBD Volume/day: 2800 ml, 3360 kcal/day. Clinical progress: From the beginning, the patient tolerates the medication and the exclusive enteral nutrition well. After treatment with Modulen IBD® for 5 weeks, the outbreak of activity remits (in a short time, a significant improvement in analytical parameters and in the nutritional condition, so, after the 6 weeks, a normal diet for his age is begun. Recovery of weight loss. He now maintains a weight of 62.2 kg (+5.3 kg in 6 weeks).

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