益生菌微生物在汞毒性修复中的有益前景展望。

Sanjib Bhattacharya
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引用次数: 0

摘要

重金属毒性对环境和人类造成了潜在的全球性威胁。汞中毒被视为严重的全球社区健康风险,因为目前还没有针对慢性汞中毒的特殊和经证实的治疗方法。益生菌包括活的致病微生物,通过口服来改善肠道微生物平衡,从而使宿主受益。科学文献表明,不同的益生菌微生物可以消除汞的毒性。本文将有关益生菌汞毒性减轻作用的实验进行汇总,探讨其机制假说。通过使用在线书目数据库进行文献审查。文献调查显示,8种益生菌微生物在临床前实验研究中显示出对汞毒性的显著保护作用。临床研究尚未有值得注意的结果报道。这些研究结果表明,益生菌微生物可能在改善和治疗汞毒性方面具有前景。益生菌补充可以作为抗汞的饮食治疗方法以及现有的治疗方法。
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An Insight into the Salutary Prospect of the Probiotic Microorganisms for the Remediation of Mercury Toxicity.

Heavy metal toxicity imposes a potential worldwide threat to environment and humans. Mercury toxicity is regarded as a serious global community health risk, as there is no particular and proven treatment for chronic mercury toxicity. Probiotics include the live apathogenic microorganisms, which are administered orally to revamp the gut microbial equilibrium thus bestowing benefit to the host. Scientific literature demonstrates different probiotic microorganisms can obviate mercurey toxicity. The present article puts together the experiments on probiotics with mercury toxicity alleviation effects in pursuit of the mechanistic hypotheses. Literature scrutiny was performed by using online bibliographic databases. Literature survey revealed that, eight types of probiotic microorganisms demonstrated significant protection from mercury toxicity in experimental pre-clinical studies. Clinical investigation with noteworthy outcome was not reported yet. Results of these studies indicate that probiotic microorganisms may hold the promise in amelioration and therapeutics of mercury toxicity. Probiotic supplementation may serve as a dietary therapeutic approach against mercurials along with extant therapies.

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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
20
审稿时长
>12 weeks
期刊介绍: The Journal of Environmental Pathology, Toxicology and Oncology publishes original research and reviews of factors and conditions that affect human and animal carcinogensis. Scientists in various fields of biological research, such as toxicologists, chemists, immunologists, pharmacologists, oncologists, pneumologists, and industrial technologists, will find this journal useful in their research on the interface between the environment, humans, and animals.
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