Marie Fiedler , Carmen Hofmann , Christian Montag , Markus Kiefer
{"title":"执行功能发展的相关因素:累积多巴胺遗传评分和环境因素预测幼儿园儿童在go/nogo任务中的表现","authors":"Marie Fiedler , Carmen Hofmann , Christian Montag , Markus Kiefer","doi":"10.1016/j.tine.2023.100200","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.</p></div><div><h3>Methods</h3><p>Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity. Dimensions of parenting behavior and parental education were assessed.</p></div><div><h3>Results</h3><p>Parental education was positively related to accuracy in nogo trials. An interaction between the cumulative genetic score and the parenting dimension Responsiveness predicted go RT indicating that children with a high cumulative genetic score and high parental responsiveness exhibited a careful response mode.</p></div><div><h3>Conclusion</h3><p>The development of EF in kindergarten children is related to parental education as well as to an interaction between the molecular-genetics of the DA system and parenting behavior.</p></div>","PeriodicalId":46228,"journal":{"name":"Trends in Neuroscience and Education","volume":"30 ","pages":"Article 100200"},"PeriodicalIF":3.4000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Factors related to the development of executive functions: A cumulative dopamine genetic score and environmental factors predict performance of kindergarten children in a go/nogo task\",\"authors\":\"Marie Fiedler , Carmen Hofmann , Christian Montag , Markus Kiefer\",\"doi\":\"10.1016/j.tine.2023.100200\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.</p></div><div><h3>Methods</h3><p>Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity. Dimensions of parenting behavior and parental education were assessed.</p></div><div><h3>Results</h3><p>Parental education was positively related to accuracy in nogo trials. An interaction between the cumulative genetic score and the parenting dimension Responsiveness predicted go RT indicating that children with a high cumulative genetic score and high parental responsiveness exhibited a careful response mode.</p></div><div><h3>Conclusion</h3><p>The development of EF in kindergarten children is related to parental education as well as to an interaction between the molecular-genetics of the DA system and parenting behavior.</p></div>\",\"PeriodicalId\":46228,\"journal\":{\"name\":\"Trends in Neuroscience and Education\",\"volume\":\"30 \",\"pages\":\"Article 100200\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Neuroscience and Education\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211949323000030\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Neuroscience and Education","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211949323000030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Factors related to the development of executive functions: A cumulative dopamine genetic score and environmental factors predict performance of kindergarten children in a go/nogo task
Background
This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.
Methods
Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity. Dimensions of parenting behavior and parental education were assessed.
Results
Parental education was positively related to accuracy in nogo trials. An interaction between the cumulative genetic score and the parenting dimension Responsiveness predicted go RT indicating that children with a high cumulative genetic score and high parental responsiveness exhibited a careful response mode.
Conclusion
The development of EF in kindergarten children is related to parental education as well as to an interaction between the molecular-genetics of the DA system and parenting behavior.
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