过敏性支气管肺真菌病不同病原菌的临床特点不同。

IF 0.9 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Yonago acta medica Pub Date : 2023-05-01 DOI:10.33160/yam.2023.05.016
Tomoya Harada, Genki Inui, Hiroki Ishikawa, Ryohei Kato, Yuriko Sueda, Yoshihiro Funaki, Miki Takata, Ryota Okazaki, Masato Morita, Shin Kitatani, Akira Yamasaki
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引用次数: 0

摘要

背景:变应性支气管肺真菌病(ABPM)发生于真菌,而不是烟曲霉。然而,非曲霉菌引起的ABPM的临床特征尚未明确。方法:回顾性分析2005年4月至2020年12月在我院就诊的所有ABPM患者。分析病原菌及临床特点。将患者分为曲霉组和非曲霉组。结果:曲霉组14例,非曲霉组5例。与曲霉组相比,非曲霉组血清免疫球蛋白E水平和肺活量显著降低。此外,非曲霉组口服皮质类固醇治疗的需求率较低,复发率较低。结论:与变应性支气管肺曲霉菌病患者相比,非曲霉菌ABPM患者的2型炎症发生率较低。
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The Clinical Characteristics of Allergic Bronchopulmonary Mycosis Differ Among Pathogenic Fungi.

Background: Allergic bronchopulmonary mycosis (ABPM) occurs with fungi, other than Aspergillus fumigatus. However, the clinical characteristics of ABPM caused by non-Aspergillus species are unspecified.

Methods: We retrospectively reviewed all patients with ABPM who visited to our hospital between April 2005 and December 2020. The causative fungi and clinical characteristics were analyzed. Patients were divided into the Aspergillus group and the non-Aspergillus group.

Results: Fourteen patients and five patients were included in the Aspergillus group and the non-Aspergillus group, respectively. Compared to the Aspergillus group, the non-Aspergillus group had a significantly low serum immunoglobulin E level and low forced vital capacity. In addition, the non-Aspergillus group had a lower rate of the requirement for oral corticosteroid treatment and a low frequency of recurrence.

Conclusion: Patients with non-Aspergillus ABPM had lower type 2 inflammation than did patients with allergic bronchopulmonary aspergillosis.

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来源期刊
Yonago acta medica
Yonago acta medica MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
1.60
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: Yonago Acta Medica (YAM) is an electronic journal specializing in medical sciences, published by Tottori University Medical Press, 86 Nishi-cho, Yonago 683-8503, Japan. The subject areas cover the following: molecular/cell biology; biochemistry; basic medicine; clinical medicine; veterinary medicine; clinical nutrition and food sciences; medical engineering; nursing sciences; laboratory medicine; clinical psychology; medical education. Basically, contributors are limited to members of Tottori University and Tottori University Hospital. Researchers outside the above-mentioned university community may also submit papers on the recommendation of a professor, an associate professor, or a junior associate professor at this university community. Articles are classified into four categories: review articles, original articles, patient reports, and short communications.
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