PSPVP与PSIBG治疗II-III期Kummell病的比较研究。

IF 1 4区 医学 Q4 ENGINEERING, BIOMEDICAL Bio-medical materials and engineering Pub Date : 2023-01-01 DOI:10.3233/BME-221456
Jian-Qiao Zhang, Zhong-You Zeng, Hui-Gen Lu, Wei Yu, Xu-Qi Hu, Wei-Shan Chen, Gang Chen
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引用次数: 0

摘要

背景:经皮后凸成形术(PKP)或经皮椎体成形术(PVP)通常用于II-III期Kummell病;然而,这些技术产生了一些复杂性。目的:比较经皮椎体成形术+骨水泥增强短节段椎弓根螺钉固定(PSPVP)与经椎弓根内植骨+椎弓根螺钉固定(PSIBG)治疗II-III期Kummell病的临床疗效和影像学结果。方法:2017年11月至2021年3月期间入院的69例患者纳入本研究;其中36例用PSPVP治疗,33例用PSIBG治疗。比较两组患者的围手术期、随访和影像学资料。结果:两组手术时间比较,差异无统计学意义(P > 0.05)。PSPVP组在切口长度、术中出血量、住院时间等方面均优于PSIBG组(P < 0.05)。两组患者相应时间点的VAS评分、ODI指数、后凸Cobb角、患椎楔角比较,差异均无统计学意义(P > 0.05)。PSIBG组术后及末次随访椎体前后缘高度均优于PSPVP组(P结论:PSPVP和PSIBG治疗II-III期Kummell病均能取得较好的早期临床疗效,PSPVP的侵袭性相对较小,但矫形效果较差,并发症较多。
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A comparative study of PSPVP and PSIBG in the treatment of stage II-III Kummell's disease.

Background: Percutaneous kyphoplasty (PKP) or percutaneous vertebroplasty (PVP) are commonly employed for Kummell's disease in stages II-III; however, these techniques produce some complications.

Objective: To compare the clinical efficacy and imaging results of percutaneous vertebroplasty + bone cement-augmented short-segment pedicle screw fixation (PSPVP) versus transpedicular intracorporeal bone grafting + pedicle screw fixation (PSIBG) in the treatment of stage II-III Kummell's disease.

Methods: A total of 69 patients admitted between November 2017 and March 2021 were included in this study; 36 of these were treated with PSPVP, and 33 were treated with PSIBG. Patients in the two groups were compared in terms of perioperative, follow-up, and imaging data.

Results: No statistically significant differences were found between the two groups in terms of operation duration (P > 0.05). However, the PSPVP group was superior to the PSIBG group in terms of incision length, intraoperative blood loss, and length of stay (P < 0.05). All patients were followed up for more than 12 months. The VAS score, height of anterior vertebral margin, kyphosis Cobb angle, wedge angle of the affected vertebra at seven days after surgery and last follow-up, and the ODI index at the last follow-up of the two groups were significantly improved compared with figures before surgery (P < 0.05). Compared with values before surgery, no statistically significant differences were found in the height of the posterior vertebral margin in the PSPVP group at seven days after surgery and at the last follow-up (P > 0.05). There were also no statistically significant differences in the VAS score, ODI index, kyphosis Cobb angle, and wedge angle of the affected vertebra between the two groups at corresponding time points (P > 0.05). The heights of the anterior and posterior vertebral margins in the PSIBG group were better than those in the PSPVP group after surgery and at the last follow-up (P < 0.05). In the PSPVP group, a pedicle screw fracture occurred in one patient two months after surgery, while an upper adjacent vertebral fracture occurred in one patient eight months after surgery.

Conclusion: Both PSPVP and PSIBG can achieve good early clinical efficacy in the treatment of stage II-III Kummell's disease, with PSPVP being relatively less invasive while producing a poorer orthopedic effect and more complications than PSIBG.

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来源期刊
Bio-medical materials and engineering
Bio-medical materials and engineering 工程技术-材料科学:生物材料
CiteScore
1.80
自引率
0.00%
发文量
73
审稿时长
6 months
期刊介绍: The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.
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