靶向治疗α-发射器放射免疫偶联物的现状

IF 1.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Current radiopharmaceuticals Pub Date : 2023-01-01 DOI:10.2174/1874471016666230106111119
Mobina Rabiei, Ahmad Reza Vaez Alaei, Hassan Yousefnia
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引用次数: 0

摘要

本文简要介绍了α发射器标记免疫偶联物在全球范围内的研究开发情况和临床应用,并对未来的发展趋势进行了展望。讨论了在医疗应用中潜在有用的α发射器放射性同位素、螯合剂和未来α放射免疫治疗感兴趣的免疫分子。本文还提出了螯合剂研究中存在的挑战和一些建议。
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Status of α-emitter Radioimmunoconjugates for Targeted Therapy.

This minireview describes the global situation of ongoing research and development and the clinical application of alpha emitter labeled immunoconjugates with various alpha emitters with an overview of the future trends. The potentially helpful alpha emitter radioisotopes for medical applications, chelators, and immunomolecules of interest for future alpha radioimmunotherapy are discussed. Challenges and some suggested future works on chelators are also presented.

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来源期刊
Current radiopharmaceuticals
Current radiopharmaceuticals PHARMACOLOGY & PHARMACY-
CiteScore
3.20
自引率
4.30%
发文量
43
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