Michelle Cork, Alexa McArthur, Helen Douglas, Fiona Wood
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引用次数: 1
Abstract
Objective: The objective of this review is to determine whether perioperative enteral feeding improves outcomes in patients with burns.
Introduction: Literature has identified many positive benefits of nutrition support for patients with burn injuries, including preservation of lean body mass, improved wound healing, reduced gastrointestinal permeability and enhanced immunity. Fasting for surgery can undermine the nutritional care of these patients by causing nutrient deficits. It may also negatively affect patient well-being and insulin resistance. Perioperative fasting is intended to protect patients from regurgitation and pulmonary aspiration. This research aims to investigate whether perioperative feeding impacts outcomes in patients with burn injuries.
Inclusion criteria: This systematic review will consider studies whose participants have a burn injury. The intervention is perioperative enteral feeding (either intragastric or post-pyloric). Patients who received perioperative feeding will be compared with patients who had enteral nutrition withheld during the perioperative period. A number of outcome measures will be investigated, including mortality, length of stay, wound infection, wound healing rate and aspiration pneumonia.
Methods: The key databases searched will be PubMed, CINAHL, Embase, Web of Science and Cochrane Central Register of Controlled Trials and Scopus. Only studies published in English will be considered. There will be no date limits. Full texts of selected studies will be retrieved and assessed against inclusion criteria. Studies that do not meet the inclusion criteria will be excluded, with reasons provided. Data synthesis will be pooled in a statistical meta-analysis. Subgroup analysis will be conducted where possible. Where statistical pooling is not possible, the findings will be presented in narrative form.
目的:本综述的目的是确定围手术期肠内喂养是否能改善烧伤患者的预后。文献表明，营养支持对烧伤患者有许多积极的好处，包括保持瘦体重，改善伤口愈合，降低胃肠道通透性和增强免疫力。手术禁食会导致营养缺乏，从而破坏这些患者的营养护理。它还可能对患者的健康和胰岛素抵抗产生负面影响。围手术期禁食旨在保护患者免受反流和肺误吸。本研究旨在探讨围手术期喂养是否会影响烧伤患者的预后。纳入标准:本系统综述将考虑受试者有烧伤的研究。干预措施是围手术期肠内喂养(胃内或幽门后)。接受围手术期喂养的患者将与围手术期停止肠内营养的患者进行比较。将调查一些结果指标，包括死亡率、住院时间、伤口感染、伤口愈合率和吸入性肺炎。方法:检索PubMed、CINAHL、Embase、Web of Science、Cochrane Central Register of Controlled Trials和Scopus等数据库。只考虑以英文发表的研究。没有日期限制。将检索选定研究的全文，并根据纳入标准进行评估。不符合纳入标准的研究将被排除，并说明原因。数据综合将汇集在统计荟萃分析中。如有可能，将进行分组分析。如果统计汇集不可能，调查结果将以叙述形式提出。系统评价注册号:PROSPERO CRD42018119034。
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