{"title":"A recommendation on the teaching of Michaelis–Menten kinetics in biochemistry courses","authors":"Andrew J. Howard","doi":"10.1002/bmb.21689","DOIUrl":null,"url":null,"abstract":"<p>Most textbooks and lecturers present Michaelis–Menten kinetics using the equation <i>v</i> = <i>V</i><sub>max</sub>[S]/(<i>K</i><sub>m</sub> + [S]). There are advantages to presenting this relationship in a slightly different form, namely <i>v</i> = <i>V</i><sub>max</sub>/{1 + (<i>K</i><sub>m</sub>/[S])}. We articulate advantages for single-substrate reactions and extend the formalism to include the three classes of bi-substrate reactions.</p>","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"51 1","pages":"39-43"},"PeriodicalIF":1.2000,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemistry and Molecular Biology Education","FirstCategoryId":"95","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bmb.21689","RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
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Abstract
Most textbooks and lecturers present Michaelis–Menten kinetics using the equation v = Vmax[S]/(Km + [S]). There are advantages to presenting this relationship in a slightly different form, namely v = Vmax/{1 + (Km/[S])}. We articulate advantages for single-substrate reactions and extend the formalism to include the three classes of bi-substrate reactions.
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