A plant mutant screen CURE integrated with core biology concepts showed effectiveness in course design and students' perceived learning gains.

IF 1.2 4区 教育学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Biochemistry and Molecular Biology Education Pub Date : 2024-10-23 DOI:10.1002/bmb.21865
Jinjie Liu, Christoph Benning
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引用次数: 0

Abstract

Course-based undergraduate research experiences (CUREs) provide students with valuable opportunities to engage in research in a classroom setting, expanding access to research opportunities for undergraduates, fostering inclusive research and learning environments, and bridging the gap between the research and education communities. While scientific practices, integral to the scientific discovery process, have been widely implemented in CUREs, there have been relatively few reports emphasizing the incorporation of core biology concepts into CURE curricula. In this study, we present a CURE that integrates core biology concepts, including genetic information flow, phenotype-genotype relationships, mutations and mutants, and structure-function relationships, within the context of mutant screening and gene loci identification. The design of this laboratory course aligns with key CURE criteria, as demonstrated by data collected through the laboratory course assessment survey (LCAS). The survey of undergraduate research experiences (SURE) demonstrates students' learning gains in both course-directed skills and transferrable skills following their participation in the CURE. Additionally, concept survey data reflect students' self-perceived understanding of the aforementioned core biological concepts. Given that genetic mutant screens are central to the study of gene function in biology, we anticipate that this CURE holds potential value for educators and researchers who are interested in designing and implementing a mutant screen CURE in their classrooms. This can be accomplished through independent research or by establishing partnerships between different units or institutions.

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植物突变体筛选 CURE 与核心生物学概念相结合,显示了课程设计的有效性和学生的学习收获。
以课程为基础的本科生研究经历(CURE)为学生提供了在课堂环境中参与研究的宝贵机会,扩大了本科生的研究机会,营造了包容性的研究和学习环境,缩小了研究界和教育界之间的差距。科学实践是科学发现过程中不可或缺的一部分,已在团结与平等教育中心广泛实施,但强调将核心生物学概念纳入团结与平等教育中心课程的报道却相对较少。在本研究中,我们介绍了一种将核心生物学概念(包括遗传信息流、表型-基因型关系、突变和突变体以及结构-功能关系)融入突变体筛选和基因位点鉴定的 CURE。实验课程评估调查(LCAS)收集的数据表明,本实验课程的设计符合 CURE 的主要标准。本科生研究经历调查(SURE)显示,学生在参加 CURE 之后,在课程指导技能和可迁移技能方面都有所收获。此外,概念调查数据反映了学生对上述核心生物学概念的自我认知理解。鉴于基因突变筛选是生物学中基因功能研究的核心,我们预计,对于有兴趣在课堂上设计和实施突变筛选 CURE 的教育工作者和研究人员来说,该 CURE 具有潜在的价值。这可以通过独立研究或在不同单位或机构之间建立合作伙伴关系来实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biochemistry and Molecular Biology Education
Biochemistry and Molecular Biology Education 生物-生化与分子生物学
CiteScore
2.60
自引率
14.30%
发文量
99
审稿时长
6-12 weeks
期刊介绍: The aim of BAMBED is to enhance teacher preparation and student learning in Biochemistry, Molecular Biology, and related sciences such as Biophysics and Cell Biology, by promoting the world-wide dissemination of educational materials. BAMBED seeks and communicates articles on many topics, including: Innovative techniques in teaching and learning. New pedagogical approaches. Research in biochemistry and molecular biology education. Reviews on emerging areas of Biochemistry and Molecular Biology to provide background for the preparation of lectures, seminars, student presentations, dissertations, etc. Historical Reviews describing "Paths to Discovery". Novel and proven laboratory experiments that have both skill-building and discovery-based characteristics. Reviews of relevant textbooks, software, and websites. Descriptions of software for educational use. Descriptions of multimedia materials such as tutorials on various aspects of biochemistry and molecular biology.
期刊最新文献
Encourage self-learning and collaborative learning through gamification during COVID-19 pandemic: A case study for teaching biochemistry. A plant mutant screen CURE integrated with core biology concepts showed effectiveness in course design and students' perceived learning gains. Using active learning methodologies to teach sequence analysis and molecular phylogeny. A BreakoutEDU for understanding gene expression in high school. A case study: Design, implementation, and evaluation of the emotions of its implementation. An undergraduate research experience in CRISPR-Cas9 mediated eukaryotic genome editing to teach fundamental biochemistry techniques.
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