M. Shuzo, K. Okada, H. Arai, R. Kanzaki, I. Shimoyama
{"title":"High Resolution and S/N Ratio Nano Probing System","authors":"M. Shuzo, K. Okada, H. Arai, R. Kanzaki, I. Shimoyama","doi":"10.1109/MEMSYS.2006.1627858","DOIUrl":null,"url":null,"abstract":"Recently, not only recording the neural activity, but also simultaneous measurement of ion concentration from a single cell is necessary for biological function analysis. We presented a nanoprobe with calcium ion measurement in a cell using fluorescence. We've improved the performance of the nanoprobe by coating the aluminum on the pipette. Our glass micropipette coated with aluminum can measure fluorescence from a smaller area. Using this nanoprobing system, the fluorescence response from a tissue was measured every 10 µ m in depth.","PeriodicalId":250831,"journal":{"name":"19th IEEE International Conference on Micro Electro Mechanical Systems","volume":"33 4","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2006-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"19th IEEE International Conference on Micro Electro Mechanical Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MEMSYS.2006.1627858","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Recently, not only recording the neural activity, but also simultaneous measurement of ion concentration from a single cell is necessary for biological function analysis. We presented a nanoprobe with calcium ion measurement in a cell using fluorescence. We've improved the performance of the nanoprobe by coating the aluminum on the pipette. Our glass micropipette coated with aluminum can measure fluorescence from a smaller area. Using this nanoprobing system, the fluorescence response from a tissue was measured every 10 µ m in depth.
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