Performance analysis of classifying localization sites of protein using data mining techniques and artificial neural networks

Md. Shahriare Satu, Tania Akter, Md. Jamal Uddin
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引用次数: 18

Abstract

Protein localization prediction is computation approach to predict where a protein resides in a cell. Accurate localization of proteins is needed to provide physiological substance for their function and aberrant localization of protein causes pathogenesis of various human diseases. E.Cott and Yeast are unicellular organism and different proteins allocate in their cell. If those protein are dislocated, then these causes various infections that affected human body adversely. So, the objective of this work is to classify proteins into different cellular localization sites based on amino acid sequences of E.Coli bacterium and Yeast In this experiment, we collect dataset of E.Coli and Yeast from data repository and preprocessed it for further processing. Then we train our dataset with several data mining classification algorithms and artificial neural networks. After classifying both dataset, we compare accuracies among different classifiers and try to find best classifiers for Protein localization sites prediction of E.Coli and Yeast dataset.
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基于数据挖掘技术和人工神经网络的蛋白质定位位点分类性能分析
蛋白质定位预测是一种预测蛋白质在细胞中位置的计算方法。蛋白质的准确定位是为其功能提供生理物质的必要条件,蛋白质的异常定位是人类各种疾病发病的原因。酵母和酵母都是单细胞生物,它们的细胞内分配着不同的蛋白质。如果这些蛋白质脱位,就会引起各种感染,对人体产生不利影响。因此,本研究的目的是基于大肠杆菌和酵母菌的氨基酸序列将蛋白质分类到不同的细胞定位位点。本实验从数据库中收集大肠杆菌和酵母菌的数据集,并对其进行预处理,以便进一步处理。然后我们用几种数据挖掘分类算法和人工神经网络来训练我们的数据集。在对这两个数据集进行分类后,我们比较了不同分类器的准确率,并试图找到大肠杆菌和酵母数据集蛋白质定位位点预测的最佳分类器。
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