Outcomes of GnRH agonist triggering in assisted reproductive technology: a systematic review

Reprodu??o & Climatério Pub Date : 2017-05-01 DOI:10.1016/j.recli.2016.07.003

Luciana Beatriz Mendes Gomes , Mário Henrique Bitar Siqueira , Eduardo Camelo de Castro

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Abstract

Objective

To make a review of studies that assessed the outcomes of GnRH agonist oocyte triggering in comparison with hCG in prevention of ovarian hyperstimulation syndrome and pregnancy rates.

Methods

A systematic review of studies presented in the following database: PUBMED, Lilacs and Scielo submitted from January 2005 to October 2015. The keywords were ovulation induction, ovarian hyperstimulation syndrome and gonadotropin releasing hormone.

Results

One hundred fifty-four articles were found. From these, twelve studies were completely analyzed. Eight fulfilled the inclusion criteria and one was included after the bibliographic review of the previous ones. From these nine submitted articles, two are retrospective and the others are prospective.

Conclusion

The use of GnRH agonist for oocyte triggering was comparable with hCG and showed low frequency of ovarian hyperstimulation syndrome.

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辅助生殖技术中GnRH激动剂触发的结果:系统综述

目的对GnRH激动剂触发卵母细胞与hCG预防卵巢过度刺激综合征和妊娠率的研究进行综述。方法系统回顾2005年1月至2015年10月在PUBMED、Lilacs和Scielo数据库中发表的研究。关键词:促排卵、卵巢过度刺激综合征、促性腺激素释放激素。结果共发现文献154篇。从这些研究中，我们对12项研究进行了全面分析。8篇符合纳入标准，1篇经文献综述后纳入。在这九篇提交的文章中，两篇是回顾性的，其他是前瞻性的。结论GnRH激动剂触发卵母细胞的效果与hCG相当，出现卵巢过度刺激综合征的频率较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reprodu??o & Climatério

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