Superior Performance of Surface Plasmon Resonance Biosensor for Recognizing of DNA Hybridization

Tarik Bin Abdul Akib, Md. Nazmuschayadat, M. B. Hossain
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引用次数: 2

Abstract

In this paper, we demonstrate numerical sketching of high-performance graphene implicated Surface plasmon resonance (SPR) biosensor for biomedical inflictions especially the recognition of DNA Hybridization. This SPR biosensor can be recognized adsorption of DNA biomolecules into the sensing medium, which is usage Attenuated total reflection (ATR) technique to find out the refractive index (RI) varied due to the adsorption of different concentration of DNA biomolecules. By determining the right shift of SPR angle and variation of minimum reflectance (Rmin) distinguishes between hybridization and single nucleotide polymorphisms (SNP). The FDTD (Finite Difference Time Domain) technique is used for comprising between hybridization and SNP events by Lumerical FDTD Software.
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表面等离子体共振生物传感器在DNA杂交识别中的优越性能
在本文中,我们展示了涉及表面等离子体共振(SPR)生物传感器的高性能石墨烯的数值草图,用于生物医学施加,特别是DNA杂交的识别。该SPR生物传感器可以识别DNA生物分子在传感介质中的吸附,利用衰减全反射(ATR)技术来发现由于吸附不同浓度的DNA生物分子而产生的折射率(RI)变化。通过测定SPR角的右移和最小反射率(Rmin)的变化来区分杂交和单核苷酸多态性(SNP)。采用时域有限差分(FDTD)技术,利用Lumerical FDTD软件对杂交事件和SNP事件进行组合。
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