Comparing cell block diagnostic results with histopathological results and some factors affecting the quality of cell blocks in the diagnosis of body cavity fluid cells at Viet Tiep Hospital

Abstract

Background/Purpose: To contrast the results of cell block diagnosis with histopathological results and describe some factors that affect the quality of cell blocks. Methods: The cross-sectional descriptive study was conducted based on the anatomical results of 106 patients of Viet Tiep Hospital Results: The cell block technique had a sensitivity of 84.4% significantly higher than the sensitivity of the cell smear of 57.8%. The specificity of both tests is above 80%. Cellblock test results were less accurate in yellow fluid samples (13.3%). Blood fluid and pink fluid samples both have over 90% accuracy. The difference was statistically significant with p<0.05. Cellblock test results were less accurate in samples with a sample count of ≤150 ml (52.9%). Samples with a greater number of specimens were over 80% accurate. The difference was statistically significant with p<0.05. There was no difference in the accuracy of cell block test results between specimens at different sites, cancer types, cancer origins, age groups, and sex of the subjects studied. Conclusion: The cell block technique improves the number of malignant diagnoses compared to histopathology, and has higher sensitivity and lower specificity than the cell smear technique. Factors related to the accuracy of cell block test results include the color of the test fluid and the number of fluids. There was no difference in the accuracy of CB test results on different specimens, different cancer types, different cancer origins, different ages, and genders.