Reports on in vivo and in vitro contribution of medicinal plants to improve the female reproductive function

Gildas Tetaping Mbemya , Luis Alberto Vieira , Francisca Geovania Canafistula , Otília Deusdênia Loiola Pessoa , Ana Paula Ribeiro Rodrigues
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引用次数: 27

Abstract

Medicinal plants are known as a prolific source of secondary metabolites which have important function both in vivo and in vitro during the ovarian folliculogenesis and steroidogenesis in many animal species. Some secondary metabolites can act as antioxidants generally through their ability to scavenge reactive oxygen species (ROS) or can regulate ovarian hormonal production. In general, these properties are responsible for the medicinal functions to treat woman infertility disorder. Some plants are constituted of biological actives substances which have been used to treat reproductive dysfunction. However, until recently, little was known about the implication of plants and/or their secondary metabolites on in vitro folliculogenesis and steroidogenesis. With the development of the technology, there is an increase implication of those substances in assisted reproductive technology (ART). The present review highlights some medicinal plants used in the treatment of woman disorders related to infertility. In addition, it provides an in vivo and in vitro overview of herbs and their active compounds with claims for improvement of ovarian activity thus showing their implication in female reproductive health care.

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药用植物对改善雌性生殖功能的体内外贡献报道
药用植物是次生代谢物的丰富来源,次生代谢物在许多动物的卵巢卵泡形成和类固醇形成过程中具有重要的体内和体外功能。一些次生代谢物通常通过清除活性氧(ROS)的能力或调节卵巢激素的产生而起到抗氧化剂的作用。总的来说,这些特性负责治疗女性不孕症的药用功能。一些植物是由生物活性物质组成的,已被用于治疗生殖功能障碍。然而,直到最近,人们对植物和/或它们的次生代谢物对体外卵泡形成和类固醇形成的影响知之甚少。随着技术的发展,这些物质在辅助生殖技术(ART)中的应用越来越广泛。本文综述了一些用于治疗与不孕有关的女性疾病的药用植物。此外,它还提供了体内和体外草药及其活性化合物的概述,声称可以改善卵巢活动,从而显示其在女性生殖保健中的意义。
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