Co-occurrence of autism spectrum disorder and very early onset schizophrenia: a case report

Duygu Kaba, P. Uran, A. Aysev
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Abstract

Co-occurrence of autism spectrum disorder and very early onset schizophrenia: a case report Very early onset schizophrenia (VEOS) is a chronic and debilitating psychiatric disorder and has received too little attention in the medical literature. Previous studies have suggested that VEOS had a tendency of a worse prognosis and outcome than adult onset schizophrenia. Autism spectrum disorder (ASD) is a life-long impairing heterogeneous disorder, characterized by severe and pervasive impairments in multiple areas of psychological development. Co-occurrence of ASD and VEOS is reported very rarely in the literature. This paper reports on a case diagnosed as ASD with a VEOS comorbidity. With this case report, it is aimed to review the differential diagnosis, common and different clinical features, neuroimaging findings and genetic and environmental etiologies of these two psychopathologies in the light of the literature.
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自闭症谱系障碍与极早发性精神分裂症共发一例报告
早发性精神分裂症(VEOS)是一种慢性衰弱性精神疾病,在医学文献中受到的关注太少。先前的研究表明,VEOS患者的预后和结局往往比成人发作的精神分裂症更差。自闭症谱系障碍(ASD)是一种终身损害的异质性障碍,其特点是在心理发展的多个领域存在严重和普遍的损害。ASD和VEOS同时出现的文献报道很少。本文报告一例诊断为ASD并伴有VEOS合并症的病例。本病例报告旨在结合文献回顾这两种精神病理的鉴别诊断、共同和不同的临床特征、神经影像学表现以及遗传和环境病因。
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