Bupropion Extended-Release Induced Spontaneous Orgasms

M. Orum, O. Eğilmez, Aysun Kalenderoglu
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Abstract

Bupropion extended-release induced spontaneous orgasms Sexual side effects are common with antidepressant use. Spontaneous orgasms have been previously described with several antidepressants. We report the case of a woman who had spontaneous orgasms after starting 300mg/day bupropion extended-release. Spontaneous orgasms ceased 4 days after stopping the bupropion extended-release. Bupropion extended-release is a norepinephrine-dopamine reuptake inhibitor. Norepinephrineand dopamine-related mechanisms may induce spontaneous orgasms. This unusual side effect should be questioned in patients who receive bupropion, as it may cause embarrassment and noncompliance.
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安非他酮缓释诱导自发性高潮
安非他酮缓释诱导自发性高潮抗抑郁药的性副作用是常见的。自发性高潮以前曾用几种抗抑郁药来描述。我们报告的情况下,一个妇女谁自发性高潮后,开始300mg/天安非他酮缓释片。停服安非他酮缓释片4天后,自发性高潮停止。安非他酮缓释片是一种去甲肾上腺素-多巴胺再摄取抑制剂。去甲肾上腺素和多巴胺相关机制可能诱导自发性高潮。服用安非他酮的患者应该质疑这种不寻常的副作用,因为它可能导致尴尬和不依从性。
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