[The quantitative assessment of the biological activity of angiogenin].

G S Komolova, A D Mashtakova, A A Klesov
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Abstract

Methods have been developed for the in vivo quantitative estimation of biological activity of angiogenin, a protein growth factor of blood vessels. The quantitative analysis of angiogenin with the methods of angiogenetic disks in isotopic modification requires nanogram amounts of the angiogenetic. The cutireaction test is less sensitive though technically simple. The methods are developed on animal (mouse and rat) tissues.

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【血管生成素生物活性的定量评价】。
血管生成素是一种血管生长蛋白因子,研究了血管生成素体内生物活性的定量测定方法。在同位素修饰血管生成盘的方法中,血管生成素的定量分析需要纳克量的血管生成素。皮肤反应测试虽然技术上简单,但灵敏度较低。这些方法是在动物(小鼠和大鼠)组织上发展起来的。
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[The quantitative assessment of the biological activity of angiogenin]. [Cyclic AMP in the kidneys of adrenalectomized and nonadrenalectomized normal rats and rats with reflex dystrophy against a background of organ denervation and a total block of the body's beta-adrenoreceptors by propranolol]. [Low-molecular heparin complex formation with the blood coagulation proteins--thrombin and fibrinogen]. [3'-->5'-exonucleases of the rat liver and the correction of replication errors]. [The pattern of the expression of homeo box-containing genes in the mesenchyme of the mammalian limb bud as a coordinate network for subsequent morphogenetic processes].
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