Modern (rational) methods for detecting genetic features of athletes

A. Zholinsky, A. I. Kadykova, V. Feshchenko, M. Hovhannisyan, A. V. Zorenko, R. Deev
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Abstract

Molecular genetic methods are an integral part of recent medicine. Polymerase chain reaction, Sanger sequencing, next-generation sequencing are widely used in many areas: diagnostics of infectious, inherited, oncological diseases, prenatal screening, study of polymorphisms that increase the risk of developing multifactorial diseases or promoting development physical qualities necessary to achieve success in sports and competitive activity. The growing demand for genotyping raises a number of ethical and social issues affecting the degree of usefulness of genotyping a healthy person and the scientific reliability of the data obtained using direct-to-consumer genetic testing.The review presents and systematizes the laboratory diagnostic methods used today to study nucleic acids that carry important information about human health and physical qualities.
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检测运动员遗传特征的现代(合理)方法
分子遗传学方法是现代医学的一个组成部分。聚合酶链反应、桑格测序、下一代测序被广泛应用于许多领域:传染病、遗传、肿瘤疾病的诊断、产前筛查、增加多因素疾病风险的多态性研究或促进在体育和竞技活动中取得成功所必需的身体素质的发展。对基因分型的日益增长的需求提出了一些伦理和社会问题,影响到对健康人进行基因分型的有用程度以及直接面向消费者的基因检测所获得的数据的科学可靠性。这篇综述介绍并系统化了目前用于研究携带有关人类健康和身体素质重要信息的核酸的实验室诊断方法。
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