Independent components analysis for fetal electrocardiogram extraction: a case for the data efficient Mermaid algorithm

Abstract

Fetal heart rate (FHR) monitoring is currently the primary methodology for antenatal determination of fetal well-being. Currently, the FHR can be detected with ultrasonography, but the additional information from fetal electrocardiogram (FECG) is only available via an invasive scalp electrode. A cost effective noninvasive monitoring through standard ECG electrodes could be used on nearly every patient in lieu of the ultrasound monitors. In this method, a number of electrodes are positioned on the abdomen of the mother to collect, simultaneously, various combinations of the signals including the heartbeats of the mother and the fetus. For accurate fetal heart-rate estimation, a clean FECG must be extracted from the collected mixtures. It is well known that this can be achieved using blind source separation (BSS) techniques. In this paper, the performance of the Mermaid algorithm, which is based on minimizing Renyi's mutual information, is evaluated on this problem of great practical importance. The effectiveness and data efficiency of Mermaid and its superiority over alternative information theoretic BSS algorithms are illustrated using artificially mixed ECG signals as well as fetal heart rate estimates in real ECG mixtures.