[A symmetrical approach to the analysis of cardiocyte electrical and contractile activity].

N V Dmitrieva
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Abstract

Based on the systemic symmetrical approach, experimentally determined parameters of action potential and contractile response of frog myocardial strip were analyzed prior to and after the administration of several physiologically active drugs (caffeine, neoepinephrine, nembutal, ouabain) into the perfusate. It was shown that the satisfactory functional state of preparation was characterized by an interrelation between parameters in the form of a harmonic proportion with relatively constant coefficient. When the functional state of subject is affected by a physiologically active substance, the interrelation between the parameters is considerably changed. Based on the analysis of the data of literature, it was found that the interrelation between temporary parameters of action potential in various structures from human heart has the form of a harmonic proportion with a constant coefficient close to the invariant of "Gold Wurf" proportion. The similarity is underlined of principles of cardiac function temporary arrangement at levels of cell, organ and organism.

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[一种分析心肌电和收缩活动的对称方法]。
基于系统对称方法,对经实验测定的几种生理活性药物(咖啡因、新肾上腺素、戊巴比妥、瓦巴因)注入灌注液前后蛙心肌条的动作电位和收缩反应参数进行了分析。结果表明,各参数之间的相互关系以系数相对恒定的调和比例的形式表现出满意的制备功能状态。当主体的功能状态受到生理活性物质的影响时,这些参数之间的相互关系发生了很大的变化。通过对文献资料的分析,发现人体心脏各结构动作电位暂态参数之间的相互关系具有近似于“金伍尔夫”比例不变量的常系数调和比例的形式。强调了心功能在细胞、器官和机体水平上临时安排原理的相似性。
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