Ting-Hsiang Wu, L. Gao, Yue Chen, Kenneth Wei, P. Chiou
{"title":"Pulsed laser triggered high speed microfluidic switch","authors":"Ting-Hsiang Wu, L. Gao, Yue Chen, Kenneth Wei, P. Chiou","doi":"10.1063/1.2998395","DOIUrl":null,"url":null,"abstract":"We report a high speed microfluidic switch capable of achieving a switching time of 70 musec. The switching mechanism is realized by exciting dynamic vapor bubbles with focused laser pulses in a microfluidic PDMS channel. A time-resolved imaging system has been constructed to capture the nanosecond transient channel wall deformation and the particle flow pattern. A switching of polystyrene microspheres in a Y channel has also been demonstrated. This ultrafast laser triggered switching mechanism has the potential to advance the sorting speed of the state-of-the-art microscale fluorescent activated cell sorting devices for two orders of magnitude.","PeriodicalId":402931,"journal":{"name":"2008 IEEE/LEOS International Conference on Optical MEMs and Nanophotonics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2008-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"43","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2008 IEEE/LEOS International Conference on Optical MEMs and Nanophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1063/1.2998395","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 43
Abstract
We report a high speed microfluidic switch capable of achieving a switching time of 70 musec. The switching mechanism is realized by exciting dynamic vapor bubbles with focused laser pulses in a microfluidic PDMS channel. A time-resolved imaging system has been constructed to capture the nanosecond transient channel wall deformation and the particle flow pattern. A switching of polystyrene microspheres in a Y channel has also been demonstrated. This ultrafast laser triggered switching mechanism has the potential to advance the sorting speed of the state-of-the-art microscale fluorescent activated cell sorting devices for two orders of magnitude.
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