Avascular osteonecrosis in a young patient with a novel coronavirus infection

T. Kirsanova, A. Meshkov, T. M. Manevich, M. Lysenko
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Abstract

COVID‑19 continues demonstrating possible complications after recovery. One of these complications is avascular osteonecrosis, which can lead to bone destruction and patient disability. Cases of the development of osteonecrosis associated with coronavirus infection were widely reported during and after the SARS epidemic in 2003. They also appear to be common in COVID‑19 infection. All patients who have recovered from COVID‑19 infection, especially who received glucocorticoids, are threaten of osteonecrosis development.We describe a case of bone necrosis in a healthy young woman without additional risk factors with a mild course of COVID, who received a short course of glucocorticoids.This is the first described case of COVID‑induced osteonecrosis in our country, although due to the large‑scale use of glucocorticoids, there are probably more such cases. Early diagnosis is important to prevent disease progression. Therefore, clinical alertness is necessary in all patients with COVID‑19.
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新型冠状病毒感染的年轻患者无血管性骨坏死
COVID - 19继续显示出康复后可能出现的并发症。其中一种并发症是无血管性骨坏死,可导致骨破坏和患者残疾。在2003年SARS流行期间和之后,与冠状病毒感染相关的骨坏死病例被广泛报道。它们在COVID - 19感染中似乎也很常见。所有从COVID - 19感染中康复的患者,特别是接受糖皮质激素治疗的患者,都有发生骨坏死的威胁。我们描述了一例无其他危险因素的健康年轻女性骨坏死病例,她患有轻度COVID,接受了短期糖皮质激素治疗。这是我国首次报道的新冠肺炎所致骨坏死病例,但由于糖皮质激素的大量使用,这类病例可能更多。早期诊断对预防疾病进展非常重要。因此,所有COVID - 19患者都必须保持临床警惕。
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