Dynamic Study of Planar Focusing for a Microfluidic Cell Sorter

Z. G. Wu, H. N. Cheang, D. Ghista, A. Liu
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Abstract

Planar focusing is widely used in lab-on-a-chip applications and devices. In the previous works, only the steady state was considered for the planar focusing. In this study, a dynamic response of planar focusing is studied using numerical simulation. From our simulation, the response time is various with different inlet velocity and focusing ratio. The results show that at small velocity, the response time is quit short and the velocity magnitude has small influence on response time. Interesting, we also found that the ratio of focusing ratio affect the response time stronger than velocity magnitude. It is useful to design and optimize planar focusing microfluidic cell sorters or other microfluidic devices.
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微流控电池分选机平面聚焦的动力学研究
平面聚焦广泛应用于芯片实验室应用和器件中。在以往的工作中,平面聚焦只考虑稳态。本文采用数值模拟方法研究了平面聚焦的动态响应。仿真结果表明,不同的进口速度和聚焦比对响应时间的影响是不同的。结果表明,在小速度下,响应时间较短,速度大小对响应时间的影响较小。有趣的是,我们还发现聚焦比比对响应时间的影响比速度量级更大。对平面聚焦微流控分选器或其他微流控装置的设计和优化具有指导意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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