Acquired long QT interval in athletes

Abstract

Long QT syndrome (LQTS) is a common disorder that leads to dramatic patient outcomes, chief among which is sudden cardiac death. This review provides detailed data on the diagnosis, prevalence, classification, etiology. The variety of causes leading to LQTS creates difficulties in the differential diagnosis of this condition and, as a result, LQTS often remains outside the attention of physicians who monitor the health of athletes. Particular attention is paid to the acquired forms of LQTS, particularly, the drug-induced form. The results of studies aimed at studying the prevalence of LQTS and the effect of drugs on the QT interval are presented. The influence of non-steroidal anti-inflammatory drugs on the QT interval is discussed in detail because they are often used by athletes. The purpose of this review is to expand understanding of the etiology of LQTS and justify the need for careful ECG screening and pharmacological monitoring in athletes.