[Basic investigation of saliva SIgA].

N Yoshida, T Kimura, M Iwamiya, A Iwamoto, M Sasada, S Ito, N Kikuchi
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Abstract

Saliva, which contributes to maintaining health in the oral environment, is affected by the physiological functions of the organism and their condition. Dental caries and periodontosis, both of which are oral diseases with frequent occurrence, require the presence of bacteria to occur. SIgA (secretory IgA), an immune globulin that is found in large quantities in substances secreted during salivation, has an antibacterial action. Thus, in conducting a basic investigation on the relationship between these factors, the author investigated what effect the speed of saliva secretion, a physiological factor of the saliva component, has on the SIgA value. Results showed that, regarding the relationship between the salivary SIgA value and the speed of salivary secretion, a negative correlation exists although this is weak in terms of relevance. The fact that the correlation displayed a tendency toward scattering indicates a need to pay attention when measuring the elements in the saliva to those factors that evidently have an effect on the composition of the saliva.

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唾液SIgA的基本研究。
唾液对维持口腔环境的健康起着重要作用,它受机体生理功能及其状况的影响。龋齿和牙周病都是口腔常见病,需要细菌的存在才会发生。SIgA(分泌型IgA)是一种免疫球蛋白,在唾液分泌过程中大量存在,具有抗菌作用。因此,在对这些因素之间的关系进行基础调查的同时,笔者考察了唾液成分的生理因素唾液分泌速度对SIgA值的影响。结果表明,唾液SIgA值与唾液分泌速度之间存在负相关关系,但相关性较弱。相关性显示出一种散射的趋势,这一事实表明,在测量唾液中的元素时,需要注意那些明显影响唾液成分的因素。
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