Células‐tronco oriundas do fluxo menstrual: possíveis aplicações

Gisela Rodrigues da Silva Sasso , Michele Longoni Calió , Luiz Fernando Portugal Fuchs , Cristiane de Paula Teixeira , Ricardo Santos Simões , Rinaldo Florencio‐Silva
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引用次数: 0

Abstract

Adult stem cells are present in several human tissues, including the endometrium. Menstrual blood derived stem cells (MenSCs) are mesenchymal stem cells that can be obtained in a non‐invasive manner. Due to its rapid proliferation rate, low immunogenicity and low tumorigenicity, MenSCs are used extensively in tissue engineering. They can be induced into multiple cell lineages under certain conditions. MenSCs contribute to tissue repair via several different mechanisms, highlighting their great promise in clinical applications. Endometrial stem cells may also be used to shed light on the pathogenesis of endometriosis and endometrial carcinoma. This review will cover recent progress in this field.

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来自月经流的干细胞:可能的应用
成体干细胞存在于包括子宫内膜在内的几种人体组织中。经血来源干细胞(MenSCs)是一种间充质干细胞,可以通过非侵入性方式获得。由于其增殖速度快、低免疫原性和低致瘤性,MenSCs在组织工程中得到了广泛的应用。在一定条件下,它们可以被诱导成多种细胞系。MenSCs通过几种不同的机制促进组织修复,突出了其在临床应用中的巨大前景。子宫内膜干细胞也可能用于阐明子宫内膜异位症和子宫内膜癌的发病机制。本次审查将涵盖这一领域的最新进展。
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