Therapeutic and Clinical Nursing Values of Momordica charantia Extracts Combined with Hedyotis diffusa on Lung Cancer

Xin Lv, Linshui Zhou, Liying Xu
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Abstract

The separation and identification of bioactive substances that come from natural resources have aroused increasing attention. Momordica charantia ( M. charantia ) has a variety of bio-activities, containing anti-oxidation, immune regulation, anti-tumor, radiation protection, anti-diabetes, and liver protection. After the extraction new substances from Momordica charantia , their treatment effect on lung cancer combined with Hedyotis diffusa was determined and the related mechanism was explored as well in this study. Firstly, the CCK-8 assay was conducted and the inhibition of the new substances combined with Hedyotis diffusa. Next, the real time RT-PCR was conducted and the relative expression of the VEGF in the cancer cells was determined. In addition, the complete chloroplast genome sequence of M. charantia is followed by the phylogenetic analysis.
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苦瓜提取物联合白花蛇舌草治疗肺癌的临床护理价值
天然资源中生物活性物质的分离与鉴定日益引起人们的重视。苦瓜(M. charantia)具有多种生物活性,含有抗氧化、调节免疫、抗肿瘤、防辐射、抗糖尿病、保护肝脏等。本研究通过从苦瓜中提取新物质,确定其对肺癌合并白花蛇舌炎的治疗效果,并探讨其作用机制。首先进行CCK-8测定,考察新物质与白花蛇舌草联用后的抑制作用。然后进行实时RT-PCR,测定VEGF在癌细胞中的相对表达量。此外,本文还对charantia叶绿体全基因组序列进行了系统发育分析。
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来源期刊
Journal of Biobased Materials and Bioenergy
Journal of Biobased Materials and Bioenergy 工程技术-材料科学:生物材料
自引率
0.00%
发文量
60
审稿时长
6 months
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