Help sought for gout sufferers: A historical look at the treatment of gout in the New Kingdom of Granada

Eduardo Tuta-Quintero , Ignacio Briceño-Balcázar , Julio César Martínez-Lozano , Claudia Mora-Karam , Álvaro Gonzales-Yunda , Lina Gómez-Restrepo , Alberto Gómez-Gutiérrez
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Abstract

Introduction

During the colonial period, despite scarce knowledge and resources, doctors and apothecaries developed medical prescriptions mainly of vegetable origin for the management of multiple diseases, including gout.

Objective

To contextualise and describe the use of medical prescription in the early 19th century in the New Kingdom of Granada for the treatment of gout.

Material and methods

A documentary search of medical prescription was carried out in the Cipriano Rodríguez Santamaría Historical Archive of the Octavio Arizmendi Posada Library of the University of La Sabana. Subsequently, an open literature review was carried out in the ScienceDirect, ClinicalKey, and Scielo databases in English and Spanish.

Results

Pistacia lentiscus, the basis of the recipe described, has a high content of terpenes, tannins, flavonoids, and coumarins, which generate anti-inflammatory, antimicrobial, antioxidant, antibiotic, antiviral, and anti-atherogenic effects, among others.

Conclusion

Mastic, one of the components of these recipes, possesses anti-inflammatory and antioxidant properties, which could explain its relative efficacy in the treatment of gout in the 19th century.

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寻求痛风患者的帮助:在格拉纳达新王国治疗痛风的历史观察
在殖民时期,尽管知识和资源匮乏,医生和药剂师还是开发了主要以蔬菜为原料的医疗处方,用于治疗多种疾病,包括痛风。背景和描述19世纪初在格拉纳达新王国治疗痛风的医学处方。在拉萨巴纳大学Octavio Arizmendi Posada图书馆的Cipriano Rodríguez Santamaría历史档案中对医疗处方进行了文献检索。随后,在ScienceDirect、ClinicalKey和Scielo数据库中进行了英语和西班牙语的公开文献综述。黄连木是上述配方的基础,含有高含量的萜烯、单宁、类黄酮和香豆素,具有抗炎、抗菌、抗氧化、抗生素、抗病毒和抗动脉粥样硬化等作用。乳胶,这些配方的成分之一,具有抗炎和抗氧化的特性,这可以解释它在19世纪治疗痛风的相对功效。Durante el periodo colonial, pese和los escasso、conconciimientos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos、modecos等。根据具体情况,说明在新格拉纳达州和新格拉纳达州,如何接收和处理与格拉纳达有关的数据。请查阅llevó a cabo una búsqueda关于在档案中收集到的文件Histórico奇普里亚诺Rodríguez Santamaría关于奥克塔维奥·阿里兹门迪·波萨达拉萨巴纳大学图书馆,Chía(哥伦比亚)。postiormente, see realizó una revisión de la literature sin límite de tiempo, en las bases de datos ScienceDirect, ClinicalKey y Scielo, en inglasses y español。黄连木,基de la receta desita, tiene unalto contenido de terpenos, taninos,黄酮类化合物通过cumarinas,抗炎,抗菌素,抗氧化剂,antibióticos,抗病毒药物通过抗黄连素,entre otros。El lentisco, uno de los componentde de estas recetas,提出丙酸酯抗炎剂的抗氧化剂的podrían明确的相对效果在治疗的糖尿病和糖尿病的治疗[j]。
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