Karotis Stenozu Tedavisinde Karotis Arter Stentleme ve Karotis Endarterektomi Yöntemlerinin Kısa Dönem Sonuçları: Randomize Kontrollü Çalışmaların Güncel Bir Meta-Analizi

Q4 Medicine Duzce Medical Journal Pub Date : 2023-10-10 DOI:10.18678/dtfd.1306382

İzzet AYDEMİR, İhsan DOĞAN, Afsun Ezel ESATOĞLU

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Abstract

Aim: Carotid artery stenting is thought to result in better outcomes when compared to carotid endarterectomy. To evaluate this hypothesis, a far-reaching of published randomized controlled trials were performed to evaluate the short-term outcomes of carotid artery stenting versus carotid endarterectomy for patients undergoing carotid artery stenosis. Material and Methods: A comprehensive search of trials published from 1994 until December 31, 2022, was performed using Science Direct, PubMed, Web of Science, Sage, Ebscohost, Scopus, and Cochrane Central electronic databases. Major endpoints (any stroke, myocardial infarction, and all-cause mortality) were extracted from the publications. Pooled risk ratio (RR) and 95% confidence interval (CI) were calculated using a fixed-effects model. Results: 21 trials involving 15518 patients (8514 with stenting, 7004 with endarterectomy) were included in the meta-analysis. Stenting was associated with a significantly increased risk of short-term any stroke (RR=1.555, 95% CI: 1.307-1.851, p

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颈动脉支架植入术和颈动脉内膜剥脱术治疗颈动脉狭窄的短期效果：随机对照试验的最新元分析

目的:与颈动脉内膜切除术相比，颈动脉支架置入术被认为具有更好的预后。为了评估这一假设，我们进行了一项广泛的已发表的随机对照试验，以评估颈动脉狭窄患者颈动脉支架置入与颈动脉内膜切除术的短期结果。材料和方法:使用Science Direct、PubMed、Web of Science、Sage、Ebscohost、Scopus和Cochrane Central电子数据库，对1994年至2022年12月31日发表的试验进行全面检索。主要终点(任何中风、心肌梗死和全因死亡率)从出版物中提取。合并风险比(RR)和95%置信区间(CI)采用固定效应模型计算。结果:21项试验涉及15518例患者(8514例支架置入，7004例动脉内膜切除术)纳入meta分析。支架植入与短期卒中风险显著增加相关(RR=1.555, 95% CI: 1.307-1.851, p

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