The relationship between febrile seizure and hematological parameters in children

Rojan Ipek, H. Almış, I. Bucak, Sumeyye Erdogan
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Abstract

Aim: The aim of this study was to investigate whether hematological parameters play a significant role in the relationship between hematological parameters and seizure occurrence in children with febrile seizures (FS) by comparing them to a healthy control group with no fever or seizures. Materials and Methods: One-hundred forty-one patients diagnosed with FS and with available a complete blood count results and a control group of 143 children were finally enrolled. Results: The study group consisted of 141 patients, 57 girls (40.4%) and 84 boys (59.6%) (M/F=1.4). Mean age at the time of first FS was 22.89 ± 13.95 months. Ninety-two (65.2%) of the study group were diagnosed with simple FS, 32 (22.7%) with complex FS, and 17 (12.1%) with febrile status epilepticus (FSE). Conclusion: Since our neutrophil, lymphocyte, eosinophil, and mean platelet volume (MPV) results were statistically significant in patients with FS, it is thought that these markers may represent potential predictive parameters in that condition.
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儿童热性惊厥与血液学参数之间的关系
目的:本研究旨在通过将发热性癫痫发作(FS)患儿与无发热或癫痫发作的健康对照组进行比较,探讨血液学参数是否在血液学参数与癫痫发作之间的关系中发挥重要作用:材料与方法:最终招募了 141 名确诊为发热性惊厥且有全血细胞计数结果的患者,以及 143 名儿童组成的对照组:研究组共有 141 名患者,其中女孩 57 名(占 40.4%),男孩 84 名(占 59.6%)(男/女=1.4)。首次接受 FS 时的平均年龄为 22.89±13.95 个月。研究组中有 92 人(65.2%)被诊断为单纯性 FS,32 人(22.7%)被诊断为复杂性 FS,17 人(12.1%)被诊断为发热性癫痫(FSE)。结论由于我们的中性粒细胞、淋巴细胞、嗜酸性粒细胞和平均血小板体积(MPV)结果在FS患者中具有统计学意义,因此认为这些标记物可能代表了该病症的潜在预测参数。
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