{"title":"Inhibitory capacity of enzyme xanthine oxidase of extract and compounds from roots of Berchemia lineata (L.) DC","authors":"Quang Ung Le, Thi-Ngoc Lanh","doi":"10.31254/jahm.2023.9305","DOIUrl":null,"url":null,"abstract":"The root of Berchemia lineata (L.) DC is used to treat rheumatoid arthritis in Vietnam. The chemical compounds and evaluation of the xanthine oxidase inhibitory capacity of root extracts were studied in this work. Two compounds of quercetin and emodin were the identified compounds in the roots. Rubrofusarin 6-O-α-L-rhamnosyl-(1 → 6)-O-β-D-glucopyranoside (compound 2) being new compounds was firstly identified in the roots. The compound 2 has highest xanthine oxidase enzyme inhibitory capacity compared to quercetin, emodin and E70.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ayurvedic and Herbal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31254/jahm.2023.9305","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The root of Berchemia lineata (L.) DC is used to treat rheumatoid arthritis in Vietnam. The chemical compounds and evaluation of the xanthine oxidase inhibitory capacity of root extracts were studied in this work. Two compounds of quercetin and emodin were the identified compounds in the roots. Rubrofusarin 6-O-α-L-rhamnosyl-(1 → 6)-O-β-D-glucopyranoside (compound 2) being new compounds was firstly identified in the roots. The compound 2 has highest xanthine oxidase enzyme inhibitory capacity compared to quercetin, emodin and E70.
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