Evaluation of antibacterial and antioxidant properties of Lavandula officinalis extracts obtained by ultrasound

Wendy Yaneth Villastrigo López, Christian Javier Cabello Alvarado, M. D. Dávila Medina, A. C. Castañeda Facio, A. S. Galindo
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Abstract

Lavandula officinalis is a Mediterranean plant to which antimicrobial and antioxidant properties are attributed. The objective of the research was to evaluate the chemical composition, antioxidant and antibacterial activity of dried leaves of Lavandula officinalis. For the extraction of bioactive compounds, ultrasound was used, which is an environmentally friendly technique, where a yield percentage of 15.51% was obtained. The chemical composition was evaluated by high-performance liquid chromatography coupled to mass (HPLC-MS), where it was demonstrated that it was possible to extract compounds such as rosmarinic acid, medioresinol, which are the main compounds to which the properties of this plant are attributed. The antioxidant evaluation was carried out by DPPH, ABTS, and FRAP, where inhibition percentages of 60.99 %, 79.86 %, and 0.07 mg Trolox/mL, respectively, were found. The antibacterial activity against Staphylococcus aureus and Escherichia coli was evaluated by the agar diffusion method, finding inhibition halos of 10 mm and 9 mm, respectively. This demonstrates that the bioactive compounds contained in Lavandula officinalis are an alternative to the synthetic compounds currently used in the cosmetic, food, and pharmaceutical industries due to the properties they possess.
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评估超声波提取的薰衣草提取物的抗菌和抗氧化特性
薰衣草是一种地中海植物,具有抗菌和抗氧化特性。研究的目的是评估薰衣草干叶的化学成分、抗氧化和抗菌活性。在提取生物活性化合物时,使用了对环境友好的超声波技术,提取率为 15.51%。通过高效液相色谱-质谱(HPLC-MS)对化学成分进行了评估,结果表明可以提取出迷迭香酸、梣酮醇等化合物,而这些化合物正是这种植物特性的主要成分。通过 DPPH、ABTS 和 FRAP 进行了抗氧化评估,发现抑制率分别为 60.99 %、79.86 % 和 0.07 毫克 Trolox/毫升。用琼脂扩散法评估了对金黄色葡萄球菌和大肠杆菌的抗菌活性,发现抑制光晕分别为 10 毫米和 9 毫米。这表明,薰衣草中所含的生物活性化合物因其所具有的特性,可替代目前用于化妆品、食品和制药行业的合成化合物。
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