Leucosceptrum canum sm.: A comprehensive review on phytochemistry, biological applications and chemophenetic values

IF 1.4 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Biochemical Systematics and Ecology Pub Date : 2024-05-21 DOI:10.1016/j.bse.2024.104849
Himani Karakoti , Ravendra Kumar , Sonu Kumar Mahawer , Om Prakash , D.S. Rawat
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Abstract

Leucosceptrum canum Sm., belonging to the Lamiaceae family, is a colorful, aromatic woody plant renowned for its nectar production. Extensive phytochemical research over the years has led to the identification of numerous chemical constituents within L. canum, particularly highlighting diterpenoids and sesterterpenoids as its characteristic compounds. L. canum has demonstrated a wide range of biological activities including antibacterial, cytotoxic, antifeedant, insecticidal, herbicidal, immunomodulatory and showed potential properties for treatment of heat stroke, anonymous swollen, impetigo, suppurative osteomyelitis, traumatic injury, and bleeding wound. Phytochemical investigation on L. canum exhibits chemophenetic significance based on its characteristic compounds. Additionally, sesterterpenoids and some other compounds serve as valuable chemotaxonomic marker of this genus, since there are no reports on their isolation from other genera and families. In the current article, the latest research progress on L. canum was reviewed to have a more comprehensive and systemic understanding of the plant. Further exploration of its pharmacological potential and elucidation of its chemical diversity could pave the way for novel applications and therapeutic interventions.

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Leucosceptrum canum sm:植物化学、生物应用和化学遗传学价值综述
茜草科茜草属(Lamiaceae)茜草属(Leucosceptrum canum Sm.)是一种色彩丰富、芳香浓郁的木本植物,以盛产花蜜而闻名。经过多年广泛的植物化学研究,L. canum 中的许多化学成分已被鉴定出来,特别是二萜类和酯类化合物是其特征化合物。L. canum 具有广泛的生物活性,包括抗菌、细胞毒、抗虫、杀虫、除草、免疫调节,并具有治疗中暑、无名肿毒、脓疱疮、化脓性骨髓炎、外伤和出血伤口的潜在特性。根据 L. canum 的特征化合物,对其进行的植物化学调查显示了其化学遗传学意义。此外,酯萜类化合物和其他一些化合物是该属植物有价值的化学分类标记,因为目前还没有从其他属和科分离出这些化合物的报告。本文对 L. canum 的最新研究进展进行了综述,以便更全面、系统地了解该植物。对其药理潜力的进一步探索以及对其化学多样性的阐明将为新的应用和治疗干预铺平道路。
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来源期刊
Biochemical Systematics and Ecology
Biochemical Systematics and Ecology 生物-进化生物学
CiteScore
3.00
自引率
12.50%
发文量
147
审稿时长
43 days
期刊介绍: Biochemical Systematics and Ecology is devoted to the publication of original papers and reviews, both submitted and invited, in two subject areas: I) the application of biochemistry to problems relating to systematic biology of organisms (biochemical systematics); II) the role of biochemistry in interactions between organisms or between an organism and its environment (biochemical ecology). In the Biochemical Systematics subject area, comparative studies of the distribution of (secondary) metabolites within a wider taxon (e.g. genus or family) are welcome. Comparative studies, encompassing multiple accessions of each of the taxa within their distribution are particularly encouraged. Welcome are also studies combining classical chemosystematic studies (such as comparative HPLC-MS or GC-MS investigations) with (macro-) molecular phylogenetic studies. Studies that involve the comparative use of compounds to help differentiate among species such as adulterants or substitutes that illustrate the applied use of chemosystematics are welcome. In contrast, studies solely employing macromolecular phylogenetic techniques (gene sequences, RAPD studies etc.) will be considered out of scope. Discouraged are manuscripts that report known or new compounds from a single source taxon without addressing a systematic hypothesis. Also considered out of scope are studies using outdated and hard to reproduce macromolecular techniques such as RAPDs in combination with standard chemosystematic techniques such as GC-FID and GC-MS.
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