Treatment of periodontal osseous defect with bio-oss xenograft and biodegradable IGF fibers: A case report

Abstract

Osseous defect caused due to periodontitis needed to be repaired or regenerated to avoid tooth loss. Bio-oss is made up of 10% porcine collagen and can induce osteoblastic differentiation due to its volumetric stability and out standing osteoconductive properties. Application of growth factors in regenerative procedures have helped to maintain the scaffold and induce several cellular processes. The biodegradable fibers incorporated with IGF growth factor has strong effect on PDL fibroblasts, mitogenesis, and protein synthesis which promotes osteogenesis and cementogenesis. A patient having grade II furcation and intrabony defect was treated and evaluated after 12 months with biodegradable fibers infused with insulin like growth factor and bio oss xeno graft irt 36. Treated site responded well to the use of the bovine bone mineral with good tissue response and an improvement and there was an overall mean probing pocket reduction in the deepest site of osseous defects. The clinical parameters assessed are plaque index, bleeding on brobing, pocket probing depth, clinical attachment level, glickman’s furcation index and RVG at baseline, 6 and 12 months post operatively. Both the bone grafts resulted in better regeneration when compared to base line and 12 months.Bio oss (bovine bone mineral) and biodegradable fibres infused with insulin like growth factor materials are of considerable promise for regeneration with better clinical and radiographic outcomes.