A Study on Suicidal Poisoning in a Tribal Area of Mahabubabad, Telangana

Sarella Prasanth Kumar, Aswan Gaddala, S. Junapudi, Professor Syam Sundar Junapudi
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Abstract

Background: Pesticide poisoning kills hundreds of thousands of people in the Asia Pacific region each year. The majority are from deliberate self-poisoning with organophosphorus pesticides (OP),paraquat etc. It is a critical health problem in rural areas, where hazardous pesticides are easily available. Very few studies were present regarding this in India and research on anti-dotes to commonly available pesticides is very minimal. According to WHO report, it is the 2nd most common cause of death among people aged 15-29 years. Methodology: An observational study was conducted to study suicidal poisoning cases from Jan-June 2022 in a retrospective record-based manner.Qualitative variables were represented with graphs and tables. Quantitative variables were represented with mean and Standard deviation. Multinomial logistic regression was done to test the significance of poisoning agents with survival status. Nagelkerke R-squared mean regression model was considered in the analysis. p-value less than 0.05 was considered significant. Results: The incidence of suicidal poisoning was 696(~0.46%) during the study period. The mean age of the study population is 32.5±12.3 years. Majority of the cases were Organophosphorus compounds and paraquat comprising a total of about 26.11%. Fatality rate was 17.4% Multinomial logistic regression of various poisoning agents showed high significance of mortality OP poisoning(p=0.03), Paraquat poisoning (p<0.001) and Herbicides(p=0.02). Conclusion: Young populations were more prone to commit suicide suggesting increased recognition of the need for a coordinated response involving public health officials and psychiatric specialists to conduct mental health awareness camps and to provide counselling. Strengthening of translational research to develop anti-dotes for commonly available pesticides.
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特伦甘纳邦马哈布巴德部落地区自杀性中毒事件研究
背景:亚太地区每年有数十万人死于农药中毒。其中大多数人是因故意使用有机磷农药(OP)、百草枯等农药自毒而死。在农村地区,危险农药很容易获得,因此这是一个严重的健康问题。印度在这方面的研究很少,对常见农药的解毒药研究也非常少。根据世界卫生组织的报告,它是 15-29 岁人群中第二大常见死因。研究方法:以回顾性记录为基础,对 2022 年 1 月至 6 月期间的自杀性中毒病例进行了观察研究。定量变量用平均数和标准差表示。多项式逻辑回归用于检验中毒剂与生存状况的相关性。分析中考虑了纳格尔克R平方均值回归模型,P值小于0.05为显著。结果在研究期间,自杀性中毒的发生率为 696(约 0.46%)。研究对象的平均年龄为 32.5±12.3 岁。大多数病例为有机磷化合物和百草枯,共占约 26.11%。死亡率为 17.4% 各种中毒剂的多项式逻辑回归显示,有机磷中毒(p=0.03)、百草枯中毒(p<0.001)和除草剂(p=0.02)的死亡率具有高度显著性。结论年轻人更容易自杀,这表明人们越来越认识到有必要采取协调一致的应对措施,让公共卫生官员和精神科专家参与进来,开展心理健康宣传营并提供咨询。加强转化研究,开发常用杀虫剂的解毒剂。
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