Marwa M. Nageeb, Amany Farouk Mohamed El Fakahany, Amina Ibrahim Abd El Maaboud, Safaa Hassanien Youssif, Fatma Ahmed Hegab, Ghada Helmy Omar
{"title":"Efficacy of Atorvastatin Loaded on Nano Particles on Cryptosporidium Parvum in Experimentally Infected Mice","authors":"Marwa M. Nageeb, Amany Farouk Mohamed El Fakahany, Amina Ibrahim Abd El Maaboud, Safaa Hassanien Youssif, Fatma Ahmed Hegab, Ghada Helmy Omar","doi":"10.21608/bmfj.2024.267590.2014","DOIUrl":null,"url":null,"abstract":": Background: Cryptosporidium parvum is an intracellular coccidial protozoa that can lead to life-threatening impacts in immunocompromised hosts. Atorvastatin may be used to treat human cryptosporidiosis. Nanomedicine developments appear promising in treatment of cryptosporidiosis. Purpose: The aim of this work is to evaluate the efficacy of atorvastatin loaded on nano-particles on treatment of cryptosporidiosis. Methods: Cryptosporidium oocysts were obtained by collection of stools from naturally infected calves. Both","PeriodicalId":503219,"journal":{"name":"Benha Medical Journal","volume":" 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Benha Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/bmfj.2024.267590.2014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
: Background: Cryptosporidium parvum is an intracellular coccidial protozoa that can lead to life-threatening impacts in immunocompromised hosts. Atorvastatin may be used to treat human cryptosporidiosis. Nanomedicine developments appear promising in treatment of cryptosporidiosis. Purpose: The aim of this work is to evaluate the efficacy of atorvastatin loaded on nano-particles on treatment of cryptosporidiosis. Methods: Cryptosporidium oocysts were obtained by collection of stools from naturally infected calves. Both
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