PCD-CT enables contrast media reduction in abdominal imaging compared to an individualized kV-adapted contrast media injection protocol on EID-CT

IF 3.2 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING European Journal of Radiology Pub Date : 2024-08-10 DOI:10.1016/j.ejrad.2024.111680

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引用次数: 0

Abstract

Objectives

This study aims to demonstrate reduced iodine contrast media (CM) in routine abdominal CT scans in portal venous phase (PVP) using a photon-counting detector CT (PCD-CT) compared to total body weight (TBW) and kV-adapted CM injection protocols on a state-of-the-art energy-integrating detector CT (EID-CT) while maintaining sufficient image quality (IQ).

Materials and Methods

Consecutive contrast-enhanced abdominal PVP CT scans from an EID-CT (Nov 2022-March 2024) and a PCD-CT (Sep 2023-Dec 2023) were compared. CM parameters (total iodine load (TIL), iodine delivery rate (IDR) and dosing factor (DF)) were reported. An individualized acquisition and CM injection protocol based on TBW and kV was applied for the EID-CT and a TBW adapted CM injection protocol was used for the PCD-CT. Objective IQ was evaluated with mean attenuation (Hounsfield Units, HU), signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR)). Subjective IQ was assessed via a 5-point Likert scale by 2 expert readers based on diagnostic confidence.

Results

Based on 91 EID-CT scans and 102 PCD-CT scans a TIL reduction of 20.1 % was observed for PCD-CT. PCD-CT demonstrated significantly higher SNR (9.9 ± 1.7 vs. 9.1 ± 1.8, p < 0.001) and CNR (5.1 ± 1.7 vs. 4.3 ± 1.3, p < 0.001) compared to EID-CT. Subjective IQ assessment showed that all scans had sufficient diagnostic IQ.

Conclusions

PCD-CT allows for CM reduction while providing higher SNR and CNR compared to EID-CT, using clinical individualized scan and CM injection protocols.

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与 EID-CT 上的个性化 kV 适应造影剂注射方案相比，PCD-CT 可在腹部成像中减少造影剂用量

目的本研究旨在证明，在保持足够图像质量（IQ）的前提下，使用光子计数探测器 CT（PCD-CT）进行门静脉相（PVP）常规腹部 CT 扫描时，与最先进的能量积分探测器 CT（EID-CT）上的总重量（TBW）和千伏适应性 CM 注入方案相比，碘造影剂（CM）的用量有所减少。材料和方法比较了来自 EID-CT （2022 年 11 月至 2024 年 3 月）和 PCD-CT （2023 年 9 月至 2023 年 12 月）的连续对比增强腹部 PVP CT 扫描。报告了 CM 参数（总碘负荷 (TIL)、碘输送率 (IDR) 和剂量系数 (DF)）。EID-CT 采用了基于 TBW 和 kV 的个性化采集和 CM 注入方案，而 PCD-CT 则采用了与 TBW 相适应的 CM 注入方案。客观智商通过平均衰减（Hounsfield 单位，HU）、信噪比（SNR）和对比度-噪声比（CNR）进行评估。）结果基于 91 次 EID-CT 扫描和 102 次 PCD-CT 扫描，观察到 PCD-CT 的 TIL 减少了 20.1%。与 EID-CT 相比，PCD-CT 的 SNR（9.9 ± 1.7 vs. 9.1 ± 1.8，p < 0.001）和 CNR（5.1 ± 1.7 vs. 4.3 ± 1.3，p < 0.001）明显更高。主观智商评估显示，所有扫描都有足够的诊断智商。结论与 EID-CT 相比，使用临床个体化扫描和 CM 注射方案，PCD-CT 可以减少 CM，同时提供更高的 SNR 和 CNR。

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来源期刊

European Journal of Radiology 医学-核医学

CiteScore

6.70

自引率

3.00%

发文量

398

审稿时长

42 days

期刊介绍： European Journal of Radiology is an international journal which aims to communicate to its readers, state-of-the-art information on imaging developments in the form of high quality original research articles and timely reviews on current developments in the field. Its audience includes clinicians at all levels of training including radiology trainees, newly qualified imaging specialists and the experienced radiologist. Its aim is to inform efficient, appropriate and evidence-based imaging practice to the benefit of patients worldwide.