European Journal of Radiology最新文献

Artificial intelligence-assisted CCTA for coronary stenosis detection: Diagnostic promise, methodological nuances, and directions for clinical translation 人工智能辅助CCTA检测冠状动脉狭窄：诊断前景、方法上的细微差别和临床翻译方向

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-13 DOI: 10.1016/j.ejrad.2026.112670

Weihao Cheng , Zekai Yu

引用次数: 0

VIPs outperforms established models for predicting post-TIPS prognosis in viral hepatitis-dominant cirrhosis VIPs在预测病毒性肝炎主导型肝硬化tips后预后方面优于现有模型

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-13 DOI: 10.1016/j.ejrad.2026.112672

Zhongsong Gao , Kun Zhang , Bo Li , Zhaogang Zhang , Hengtao Zhang , Xin Zhang , Bo Feng , Ruihang Wang , Wen Shen , Kefeng Jia

Background

Transjugular intrahepatic portosystemic shunt (TIPS) manages portal hypertension complications in cirrhosis, but predicting post-TIPS outcomes remains challenging, especially in viral hepatitis-dominated populations.

Purpose

To systematically evaluate the predictive performance of the novel Viral-Associated Index of Post-TIPS Score (VIPs) for post-TIPS prognosis. We also comprehensively compare it with six established clinical prognostic models and one imaging-based model (the spleen volume-based model, SvBM).

Materials and methods

We retrospectively analyzed 247 cirrhotic patients undergoing TIPS (56.7 % viral hepatitis). Baseline data calculated prognostic scores (VIPs, MELD, MELD-Na, FIPS, Child-Pugh, ALBI, MOTS, and SvBM). The primary endpoint was transplant-free survival (TFS). Discrimination was assessed by the area under the receiver operating characteristic curve (AUROC) at 6, 12, 36, and 60 months post-TIPS. Calibration (Brier score), explanatory power (R²), and decision curve analysis (DCA) were also evaluated.

Results

VIPs demonstrated good-to-moderate discrimination for TFS, with AUROCs (95 % CI) of 0.794 (0.689–0.899), 0.753 (0.649–0.858), 0.721 (0.645–0.797), and 0.692 (0.617–0.767) at 6, 12, 36, and 60 months, respectively. This advantage was most pronounced in the viral hepatitis subgroup, with AUROCs ranging from 0.699 (0.603–0.796) to 0.822 (0.715–0.930) across follow-up. VIPs significantly outperformed Child-Pugh, ALBI, FIPS, MOTS and SvBM at all timepoints (all p < 0.05), and surpassed MELD and MELD-Na for long-term predictions (36/60 months, both p < 0.05). It also exhibited the best calibration (lowest Brier scores: 0.076–0.217) and the highest explanatory power (R² = 0.121–0.142). Subgroup analyses further confirmed robust performance in females and patients with variceal bleeding.

Conclusions

VIPs demonstrates superior predictive accuracy for post-TIPS survival in a viral hepatitis-dominated cohort and may serve as a preferred prognostic tool to guide individualized decision-making.

背景：经颈静脉肝内门静脉系统分流术（TIPS）可治疗肝硬化门静脉高压并发症，但预测TIPS后的预后仍然具有挑战性，特别是在病毒性肝炎为主的人群中。目的系统评价新型tips后病毒相关指数评分（VIPs）对tips后预后的预测效果。我们还将其与六种已建立的临床预后模型和一种基于影像学的模型（脾体积模型，SvBM）进行了综合比较。材料和方法回顾性分析247例接受TIPS治疗的肝硬化患者（56.7%为病毒性肝炎）。基线数据计算预后评分（vip、MELD、MELD- na、FIPS、Child-Pugh、ALBI、MOTS和SvBM）。主要终点是无移植生存期（TFS）。在tips后6、12、36和60个月，通过受试者工作特征曲线下面积（AUROC）来评估辨别力。校正（Brier评分）、解释能力（R2）和决策曲线分析（DCA）也进行了评估。结果vip对TFS表现出良好到中度的区分，在6、12、36和60个月时，auroc （95% CI）分别为0.794（0.689-0.899）、0.753（0.649-0.858）、0.721（0.645-0.797）和0.692（0.617-0.767）。这一优势在病毒性肝炎亚组中最为明显，随访期间auroc范围为0.699（0.603-0.796）至0.822（0.715-0.930）。VIPs在所有时间点上的表现都明显优于Child-Pugh、ALBI、FIPS、MOTS和SvBM（均p <； 0.05），并且在长期预测方面超过MELD和MELD- na（36/60个月，均p <； 0.05）。其校正效果最佳（最低Brier评分为0.076 ~ 0.217），解释能力最高（R2 = 0.121 ~ 0.142）。亚组分析进一步证实了在女性和静脉曲张出血患者中的良好表现。结论：在病毒性肝炎为主的队列中，vip对tips后患者的生存具有优越的预测准确性，可作为指导个体化决策的首选预后工具。

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引用次数: 0

Impact of DSA-based postoperative cerebral blood flow cascades on outcomes in acute ischemic stroke patients undergoing successful endovascular thrombectomy 基于dsa的术后脑血流级联对成功进行血管内血栓切除术的急性缺血性卒中患者预后的影响

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-11 DOI: 10.1016/j.ejrad.2026.112664

Jin Liu , Chen Gong , Yuetao Wen , Jing Guo , Junling Fu , You Wang , Jinxian Yuan , Tao Xu , Lina Zhang , Shuyu Jiang

Background

Half of patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO) fail to achieve functional independence after endovascular treatment (EVT), which may be related to the ineffective restoration of cerebral blood flow in ischemic brain tissue despite revascularization. Therefore, a comprehensive model to assess postoperative cerebral blood flow cascade (pCBF) may provide additional information for treatment.

Methods

This was a retrospective cohort study. All patients underwent standard cerebral angiography immediately after EVT. pCBF consisted of expanded Thrombolysis in Cerebral Infarction, microvascular cerebral circulation time, and Cortical Vein Opacification Score based on immediate DSA images after EVT. The primary outcome was functional independence at 90 days, defined as an mRS score of 0–2.

Results

156 patients were enrolled in this study after strict screening. In multivariate regression analysis, compared with the unfavorable pCBF group, the favorable pCBF group had a higher rate of functional independence at 90 days (82.1 % vs 26.0 %, aOR 12.94, 95 % CI 5.28–31.73, P < 0.001). In addition, the pCBF demonstrated good discrimination and calibration in this cohort, as well as the fivefold cross-validation.

Conclusion

Favorable pCBF may better reflect true reperfusion in AIS-LVO patients after achieving successful recanalization and was associated with functional outcomes.

背景大血管闭塞（AIS-LVO）所致急性缺血性脑卒中患者中，有一半患者在血管内治疗（EVT）后未能实现功能独立，这可能与尽管进行了血运重建，但缺血脑组织的脑血流未能恢复有关。因此，一个综合的模型来评估术后脑血流级联（pCBF）可能为治疗提供额外的信息。方法回顾性队列研究。所有患者在EVT后立即接受标准脑血管造影。pCBF包括脑梗死扩大溶栓、微血管脑循环时间、EVT后即刻DSA图像皮质静脉混浊评分。主要终点是90天的功能独立性，定义为mRS评分0-2。结果156例患者经严格筛选入组。多因素回归分析显示，与不良pCBF组相比，不良pCBF组90天功能独立率更高（82.1% vs 26.0%, aOR 12.94, 95% CI 5.28-31.73, P < 0.001）。此外，pCBF在该队列中表现出良好的判别和校准，以及五倍交叉验证。结论良好的pCBF能更好地反映AIS-LVO患者再通成功后的真实再灌注情况，并与功能预后相关。

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引用次数: 0

Economic evaluation of bulk packaging and single-dose packaging of contrast media for contrast-enhanced CT 增强CT造影剂散装包装和单剂量包装的经济评价

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-10 DOI: 10.1016/j.ejrad.2026.112665

Jie Jia , Yuxin Peng , Zhixu Zhu , Dunming Xiao , Yingyao Chen , Yan Wei

Objective

To conduct an economic evaluation of bulk-packaged contrast media in the CT rooms from multiple perspectives, assess its economic benefits, and provide a evidence to support hospital cost control and pharmacy management.

Methods

Based on on-site investigations and the database constructed by the hospital management information system, information from 1,169 patients regarding contrast media utilization and medical insurance reimbursements was analyzed. We assessed the impact of different contrast media packaging formats on the hospital’s scanning volume and waste disposal costs using descriptive statistical methods and a decision-tree mode. In addition, cost-minimization analysis was conducted for the economic evaluation.

Results

Based on the average number of scans per hospital (49,807 per year), the 500 ml (400 mg/ml) vial saved an average of 29.60 s per patient compared with the 100 ml (400 mg/ml) vial, resulting in an annual increase of 3,890 patients scanned and potentially generating additional hospital revenue of approximately US$424,163, assuming sufficient appointment availability and operational capacity. In addition, the 500 ml (400 mg/ml) vial reduced medical insurance expenditures by US$1,701,280 to US$1,804,260 annually per hospital (a reduction of 52.19%–55.38%). The switch to bulk packaging also reduced medical waste by an average of 3,832 kg per year, corresponding to savings of US$1,904 in waste disposal costs. Qualitative interview indicated that imaging bulk-packaged contrast media can simultaneously reduce hospital costs and maintain patient safety under current technological conditions.

Conclusion

The use of bulk-packaged contrast media in contrast-enhanced CT was shown to be more effective in controlling hospital costs compared with single-dose packaging.

目的从多个角度对CT室散装包装造影剂进行经济评价，评价其经济效益，为医院成本控制和药房管理提供依据。方法通过现场调查和医院管理信息系统建立的数据库，对1169例患者的造影剂使用情况和医保报销情况进行分析。我们使用描述性统计方法和决策树模型评估了不同造影剂包装格式对医院扫描量和废物处理成本的影响。并进行了成本最小化分析，进行了经济性评价。结果：根据每家医院的平均扫描次数（每年49,807次），500毫升（400毫克/毫升）小瓶比100毫升（400毫克/毫升）小瓶平均每位患者节省29.60秒，导致每年增加3,890名扫描患者，并可能产生约424,163美元的额外医院收入，假设有足够的预约可用性和运营能力。此外，500毫升（400毫克/毫升）小瓶使每家医院每年的医疗保险支出减少1 701 280至1 804 260美元（减少52.19%-55.38%）。改用散装包装还使医疗废物平均每年减少3 832公斤，相当于节省1 904美元的废物处理费用。定性访谈表明，在目前的技术条件下，成像散装包装造影剂可以同时降低医院成本和维护患者安全。结论在增强CT中使用散装包装造影剂比单剂量包装更能有效控制医院费用。

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引用次数: 0

Navigating the complexities of recall rates in breast cancer screening: Insights from the Irish national breast cancer screening programme 导航乳腺癌筛查中召回率的复杂性：来自爱尔兰国家乳腺癌筛查计划的见解

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-08 DOI: 10.1016/j.ejrad.2026.112663

Nuala A. Healy

引用次数: 0

Letter to the Editor regarding “Allergological evaluation of hypersensitivity reactions after administration of contrast agents: What the radiologist needs to know” – The role of polyethylene glycol in contrast-induced hypersensitivity 致编辑的关于“造影剂使用后超敏反应的过敏学评估：放射科医生需要知道的”的信-聚乙二醇在造影剂引起的超敏反应中的作用

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-08 DOI: 10.1016/j.ejrad.2025.112650

Igor Rubinić , Dominik Strikić , Marija Kurtov , Viktorija Erdeljić Turk

引用次数: 0

A comprehensive quantitative and qualitative assessment of TGSE-BLADE DWI in postoperative imaging following intracranial tumor resection TGSE-BLADE DWI在颅内肿瘤切除术后影像学中的综合定量和定性评价

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-07 DOI: 10.1016/j.ejrad.2026.112659

Christer Ruff , Till-Karsten Hauser , Paula Bombach , Daniel Vogl , Constantin Roder , Frank Paulsen , Deborah Staber , Vivien Richter , Leonie Zerweck , Ulrike Ernemann , Georg Gohla

Purpose

Postoperative MRI plays a pivotal role in assessing residual disease and planning therapy after intracranial tumor resection. As acute perioperative infarction may mimic enhancing and non-enhancing tumor tissue in follow-up imaging, the initial postoperative MRI examination is essential for this purpose. However, conventional DWI techniques like RESOLVE are often impaired by artifacts from intracranial air. This study compares RESOLVE DWI with TGSE-BLADE DWI within early postoperative scans to improve diagnostic confidence in identifying ischemic changes.

Method

In a retrospective, institutional review board–approved study, 33 patients (mean age 52.3 ± 25.1 years) underwent a 1.5-Tesla MRI within 48 h of resection. RESOLVE and TGSE-BLADE DWI sequences were acquired in the same orientation and slice thickness of 5 mm. Two neuroradiologists blindly evaluated geometric distortion, susceptibility artifacts, overall image quality, and diagnostic confidence. Quantitative analysis included measuring signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values, image quality metrics and resection defect dimensions against T1-weighted images.

Results

TGSE-BLADE DWI exhibited significantly reduced geometric distortions and susceptibility artifacts near the resection site compared with RESOLVE DWI, producing superior qualitative image quality and diagnostic confidence (p < 0.001). Conversely, RESOLVE DWI yielded slightly higher SNR and CNR. Measurements of the resection defect on TGSE-BLADE DWI closely matched those on T1-weighted images (p = 0.974), while RESOLVE DWI showed a significant discrepancy (p < 0.001).

Conclusions

TGSE-BLADE DWI significantly minimizes artifacts and geometric distortions in intracranial postoperative imaging, thereby improving the detection of perioperative ischemic changes. This robust technique serves as an effective alternative to conventional EPI-based sequences in challenging settings with pronounced B₀ inhomogeneities, ultimately enhancing diagnostic confidence and patient care.

目的术后MRI在颅内肿瘤切除术后残留病变评估和治疗规划中发挥关键作用。由于急性围手术期梗死可能在随访成像中模拟增强和非增强肿瘤组织，因此术后初始MRI检查至关重要。然而，像RESOLVE这样的传统DWI技术经常受到颅内空气伪影的损害。本研究比较了术后早期扫描中的RESOLVE DWI和TGSE-BLADE DWI，以提高诊断缺血性改变的信心。方法在一项回顾性研究中，33例患者（平均年龄52.3±25.1岁）在切除后48小时内接受了1.5特斯拉MRI检查。在相同的方向和5 mm的切片厚度下获得RESOLVE和TGSE-BLADE DWI序列。两名神经放射学家盲目地评估几何畸变、敏感性伪影、整体图像质量和诊断信心。定量分析包括测量信噪比（SNR）、噪比（CNR）、表观扩散系数（ADC）值、图像质量指标和针对t1加权图像的切除缺陷尺寸。结果与RESOLVE DWI相比，stgse - blade DWI在切除部位附近的几何畸变和敏感性伪影明显减少，产生了更好的定性图像质量和诊断置信度（p < 0.001）。相反，RESOLVE DWI产生略高的信噪比和信噪比。TGSE-BLADE DWI上切除缺损的测量结果与t1加权图像非常吻合（p = 0.974），而RESOLVE DWI显示显著差异（p < 0.001）。结论stgse - blade DWI可明显减少术后颅内图像的伪影和几何畸变，提高围手术期缺血性改变的检测水平。这种强大的技术可以作为传统epi序列的有效替代方案，在具有明显B0不均匀性的具有挑战性的环境中，最终提高诊断信心和患者护理。

{"title":"A comprehensive quantitative and qualitative assessment of TGSE-BLADE DWI in postoperative imaging following intracranial tumor resection","authors":"Christer Ruff , Till-Karsten Hauser , Paula Bombach , Daniel Vogl , Constantin Roder , Frank Paulsen , Deborah Staber , Vivien Richter , Leonie Zerweck , Ulrike Ernemann , Georg Gohla","doi":"10.1016/j.ejrad.2026.112659","DOIUrl":"10.1016/j.ejrad.2026.112659","url":null,"abstract":"<div><h3>Purpose</h3><div>Postoperative MRI plays a pivotal role in assessing residual disease and planning therapy after intracranial tumor resection. As acute perioperative infarction may mimic enhancing and non-enhancing tumor tissue in follow-up imaging, the initial postoperative MRI examination is essential for this purpose. However, conventional DWI techniques like RESOLVE are often impaired by artifacts from intracranial air. This study compares RESOLVE DWI with TGSE-BLADE DWI within early postoperative scans to improve diagnostic confidence in identifying ischemic changes.</div></div><div><h3>Method</h3><div>In a retrospective, institutional review board–approved study, 33 patients (mean age 52.3 ± 25.1 years) underwent a 1.5-Tesla MRI within 48 h of resection. RESOLVE and TGSE-BLADE DWI sequences were acquired in the same orientation and slice thickness of 5 mm. Two neuroradiologists blindly evaluated geometric distortion, susceptibility artifacts, overall image quality, and diagnostic confidence. Quantitative analysis included measuring signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values, image quality metrics and resection defect dimensions against T1-weighted images.</div></div><div><h3>Results</h3><div>TGSE-BLADE DWI exhibited significantly reduced geometric distortions and susceptibility artifacts near the resection site compared with RESOLVE DWI, producing superior qualitative image quality and diagnostic confidence (p < 0.001). Conversely, RESOLVE DWI yielded slightly higher SNR and CNR. Measurements of the resection defect on TGSE-BLADE DWI closely matched those on T1-weighted images (p = 0.974), while RESOLVE DWI showed a significant discrepancy (p < 0.001).</div></div><div><h3>Conclusions</h3><div>TGSE-BLADE DWI significantly minimizes artifacts and geometric distortions in intracranial postoperative imaging, thereby improving the detection of perioperative ischemic changes. This robust technique serves as an effective alternative to conventional EPI-based sequences in challenging settings with pronounced B<sub>0</sub> inhomogeneities, ultimately enhancing diagnostic confidence and patient care.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112659"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal predictive value of MOLLI T1 mapping imaging for minimal clinically important difference after surgery for cervical spondylotic myelopathy MOLLI T1成像对脊髓型颈椎病术后最小临床重要差异的纵向预测价值。

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-07 DOI: 10.1016/j.ejrad.2026.112660

Ruo-Yu Wang , Xiao-Dan Mu , Yu-Jin Zhang , Yi-Fei Peng , Yue Liu , Zi-Bo Wang , Wei Yan , Li Zhang

Objective

To investigate the predictive value of MOLLI T₁ mapping imaging for the longitudinal changes in Minimal Clinical Important Difference (MCID) after surgery for patients with Cervical Spondylotic Myelopathy (CSM).

Methods

A prospective study enrolled 163 surgically treated CSM patients (October 2022–October 2023). All underwent preoperative conventional MRI and MOLLI T₁ mapping. The MCID was determined based on the difference in Modified Japanese Orthopedic Association (m JOA) scores before and at 3, 6, and 12 months after surgery. Patients with an MCID less than 2 were defined as the poor prognosis group, while those with an MCID of 2 or higher were defined as the good prognosis group. Patients were classified into the good prognosis and poor prognosis groups at 3, 6,12 months postoperatively. The differences in conventional MRI features and T₁ values between the two groups at these time points were compared. Univariate and multivariate logistic regression identified recovery predictors, with forest plots generated. Receiver operating characteristic (ROC) curve analysis assessed diagnostic performance.

Results

At 3 months, (27 good vs 136 poor). Only T₂WI hyperintensity differed between groups [Area under the receiver operating characteristic curve (AUC)=0.597, cut off = 0.1942; sensitivity = 40.74 %, specificity = 78.68 %]. At 6 months (60 good vs 103 poor), T₁ values showed significance (AUC = 0.690, cut off = 0.3091; sensitivity = 83.33 %, specificity = 47.57 %). At 12 months (100 good vs 63 poor), T₁ values demonstrated superior prediction (AUC = 0.875,cut off = 0.6389; sensitivity = 75.00 %, specificity = 88.89 %).

Conclusion

MOLLI T₁ mapping effectively predicts CSM recovery at 6,12 months postoperatively, with optimal diagnostic performance at 12 months.

Critical relevance statement

This study first employs MRI T₁ mapping to predict MCID outcomes in CSM patients, demonstrating its high predictive value for favorable postoperative prognosis and providing a reliable imaging parameter for outcome assessment.

目的：探讨MOLLI T1成像对脊髓型颈椎病（CSM）患者术后最小临床重要差异（MCID）纵向变化的预测价值。方法：一项前瞻性研究，纳入163例手术治疗的CSM患者（2022年10月至2023年10月）。所有患者术前均行常规MRI和MOLLI T1制图。MCID是根据手术前、术后3个月、6个月和12个月修正日本骨科协会（m JOA）评分的差异来确定的。MCID小于2定义为预后不良组，MCID大于等于2定义为预后良好组。术后3、6、12个月分为预后良好组和预后不良组。比较两组在这些时间点的常规MRI特征和T1值的差异。单变量和多变量逻辑回归确定了恢复预测因子，并生成了森林样地。受试者工作特征（ROC）曲线分析评估诊断效果。结果：3个月时，27例良好，136例不良。两组间仅有T2WI高信号差异[受试者工作特征曲线下面积（Area under receiver operating characteristic curve， AUC）=0.597, cut off = 0.1942；敏感性= 40.74%，特异性= 78.68%。6个月时，T1值具有显著性（AUC = 0.690, cut off = 0.3091；敏感性= 83.33%，特异性= 47.57%）。在12个月时，T1值显示出较好的预测（AUC = 0.875,cut off = 0.6389；敏感性= 75.00%，特异性= 88.89%）。结论：MOLLI T1映射能有效预测术后6、12个月的CSM恢复情况，12个月时诊断效果最佳。关键相关性声明：本研究首次采用MRI T1定位预测CSM患者的MCID结局，显示了其对术后良好预后的高预测价值，为结局评估提供了可靠的影像学参数。

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引用次数: 0

Noninvasive MRI assessment of cerebrospinal fluid pressure in different phases of Ménière’s disease: a prospective study 一项前瞻性研究：无创MRI评估msamimni<e:1>病不同阶段的脑脊液压力

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-06 DOI: 10.1016/j.ejrad.2026.112658

Yongjia Chen , Lu Jiang , Zequn Nie , Jing Liu , Bo Pang , Shuai Zhang , Yijiang Bai , Heng Liu , Zihang Guo , Jilin Nie , Shuangyuan Zhou , Lingyun Mei

Objectives

This study aimed to determine whether there are differences of cerebrospinal fluid pressure (CSF-P) on patients with Ménière’s disease (MD) during different phases.

Methods

Noninvasive CSF-P measurement was performed using MRI with a fat-suppressed fast recovery fast spin echo T2-weighted sequence, with the optic nerve subarachnoid space width (ONSASW) posterior to the globe serving as an indicator. Endolymphatic hydrops (EH) grades and hearing thresholds were analysed to investigate the potential correlations with CSF-P.

Results

A total of 66 participants were included. At the location of 3 mm behind the globe, the ONSASW and CSF-P were significantly smaller in the acute phase of MD group compared to both the remission phase of MD group (p < 0.001, p = 0.005, respectively) and control group (p < 0.001, p = 0.043, respectively). No statistically significant differences were found between the remission phase of MD group and the control group (both p > 0.05). Statistically significant correlation between CSF-P and hearing threshold was exclusively observed during the acute phase, with a correlation coefficient of 0.479 (p = 0.024). No significant associations between CSF-P and EH grades in both the two MD groups (all p > 0.05).

Conclusion

The study suggests that patients with MD experience a reduction in intracranial pressure during acute episodes, and these fluctuations may indicate hearing threshold variations in early-stage of patients.

目的探讨mims患者脑脊液压（CSF-P）在不同时期是否存在差异。方法以视神经球后蛛网膜下腔间隙宽度（ONSASW）为指标，采用脂肪抑制快速恢复快速旋转回声t2加权序列进行无创CSF-P测量。分析内淋巴积液（EH）等级和听力阈值，以探讨与CSF-P的潜在相关性。结果共纳入66例受试者。在地球仪后3mm位置，MD组急性期的ONSASW和CSF-P明显小于MD组缓解期（p < 0.001, p = 0.005，分别）和对照组（p < 0.001, p = 0.043）。MD组缓解期与对照组比较差异无统计学意义（p > 0.05）。CSF-P与听阈仅在急性期有统计学意义相关，相关系数为0.479 （p = 0.024）。两组患者CSF-P和EH分级之间无显著相关性（均p >； 0.05）。结论MD患者急性发作时颅内压降低，这种波动可能提示早期患者的听阈变化。

{"title":"Noninvasive MRI assessment of cerebrospinal fluid pressure in different phases of Ménière’s disease: a prospective study","authors":"Yongjia Chen , Lu Jiang , Zequn Nie , Jing Liu , Bo Pang , Shuai Zhang , Yijiang Bai , Heng Liu , Zihang Guo , Jilin Nie , Shuangyuan Zhou , Lingyun Mei","doi":"10.1016/j.ejrad.2026.112658","DOIUrl":"10.1016/j.ejrad.2026.112658","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to determine whether there are differences of cerebrospinal fluid pressure (CSF-P) on patients with Ménière’s disease (MD) during different phases.</div></div><div><h3>Methods</h3><div>Noninvasive CSF-P measurement was performed using MRI with a fat-suppressed fast recovery fast spin echo T2-weighted sequence, with the optic nerve subarachnoid space width (ONSASW) posterior to the globe serving as an indicator. Endolymphatic hydrops (EH) grades and hearing thresholds were analysed to investigate the potential correlations with CSF-P.</div></div><div><h3>Results</h3><div>A total of 66 participants were included. At the location of 3 mm behind the globe, the ONSASW and CSF-P were significantly smaller in the acute phase of MD group compared to both the remission phase of MD group (<em>p</em> < 0.001, <em>p</em> = 0.005, respectively) and control group (<em>p</em> < 0.001, <em>p</em> = 0.043, respectively). No statistically significant differences were found between the remission phase of MD group and the control group (both <em>p</em> > 0.05). Statistically significant correlation between CSF-P and hearing threshold was exclusively observed during the acute phase, with a correlation coefficient of 0.479 (<em>p</em> = 0.024). No significant associations between CSF-P and EH grades in both the two MD groups (all <em>p</em> > 0.05).</div></div><div><h3>Conclusion</h3><div>The study suggests that patients with MD experience a reduction in intracranial pressure during acute episodes, and these fluctuations may indicate hearing threshold variations in early-stage of patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"195 ","pages":"Article 112658"},"PeriodicalIF":3.3,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robotic navigation-assisted radio-frequency ablation of lung tumors: a pilot study 机器人导航辅助射频消融肺肿瘤：一项初步研究。

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology

Pub Date : 2026-01-04 DOI: 10.1016/j.ejrad.2026.112655

Yi Fang , Milan Sigdel , Manoj Sigdel , Madan Sigdel , Roshan Bhattarai , Mikias Legesse Gebremedhin , Zhanguo Sun , Xinwei Han , Dechao Jiao

Purpose

To evaluate the feasibility and safety of percutaneous radiofrequency ablation (RFA) of lung tumors under the guidance of robotic navigation system.

Material and methods

From January 2022 to December 2023, 62 cases with solitary lung tumors who underwent RFA procedure at our department and were divided into two groups: the robotic navigation assisted puncture (RNAP) group (n = 26) and manual puncture (MP) group (n = 36). Two groups were compared in terms of technical success (TS), puncture scoring (PS), CT scan times, Total procedure time (TPT), puncture time (PT), radiation exposure (RE), complete ablation (CA) rate and local tumor progression rate (LTP) rate.

Results

PS, PT, total number of CT scans, and RE showed significance between patients in the RNAP compared to those in the MP group (15/8/2/1 vs. 6/8/18/4, P = <0.001; 13.71 min vs. 16.97 mins, P < 0.01; 4.57 vs 6.94, P < 0.01; 2215.38 vs. 4615 mGy.cm, P < 0.01). TS, TPT, major complications, CA rate and LTP rate showed no difference (100 % vs.100 %; 40.52 min vs. 42.53 min; 11.53 % vs. 11.11 %; 88.46 % vs. 86.11 %; 11.53 % % vs. 13.88 %; respectively, and all P > 0.05).

Conclusions

Robotic navigation-assisted radiofrequency ablation of lung tumors is a feasible and safe technique. It can minimize needle adjustments, thereby shortening puncture time and reducing radiation exposure for patients.

目的：评价机器人导航系统引导下经皮肺肿瘤射频消融（RFA）的可行性和安全性。材料与方法：选取2022年1月至2023年12月在我科行RFA手术的孤立性肺肿瘤62例，分为机器人导航辅助穿刺（RNAP）组（n = 26）和手动穿刺（MP）组（n = 36）。比较两组手术技术成功率（TS）、穿刺评分（PS）、CT扫描次数、总手术时间（TPT）、穿刺时间（PT）、放射暴露（RE）、完全消融（CA）率和局部肿瘤进展率（LTP）率。结果：与MP组相比，RNAP组患者的PS、PT、CT扫描总次数、RE差异有统计学意义（15/8/2/1 vs 6/8/18/4, P = 0.05）。结论：机器人导航辅助射频消融治疗肺肿瘤是一种安全可行的技术。它可以减少针的调整，从而缩短穿刺时间，减少患者的辐射暴露。

{"title":"Robotic navigation-assisted radio-frequency ablation of lung tumors: a pilot study","authors":"Yi Fang , Milan Sigdel , Manoj Sigdel , Madan Sigdel , Roshan Bhattarai , Mikias Legesse Gebremedhin , Zhanguo Sun , Xinwei Han , Dechao Jiao","doi":"10.1016/j.ejrad.2026.112655","DOIUrl":"10.1016/j.ejrad.2026.112655","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the feasibility and safety of percutaneous radiofrequency ablation (RFA) of lung tumors under the guidance of robotic navigation system.</div></div><div><h3>Material and methods</h3><div>From January 2022 to December 2023, 62 cases with solitary lung tumors who underwent RFA procedure at our department and were divided into two groups: the robotic navigation assisted puncture (RNAP) group (n = 26) and manual puncture (MP) group (n = 36). Two groups were compared in terms of technical success (TS), puncture scoring (PS), CT scan times, Total procedure time (TPT), puncture time (PT), radiation exposure (RE), complete ablation (CA) rate and local tumor progression rate (LTP) rate.</div></div><div><h3>Results</h3><div>PS, PT, total number of CT scans, and RE showed significance between patients in the RNAP compared to those in the MP group (15/8/2/1 vs. 6/8/18/4, P = <strong><0.001</strong>; 13.71 min vs. 16.97 mins, P <strong>< 0.01</strong>; 4.57 vs 6.94, P <strong>< 0.01</strong>; 2215.38 vs. 4615 mGy.cm, P <strong>< 0.01</strong>). TS, TPT, major complications, CA rate and LTP rate showed no difference (100 % vs.100 %; 40.52 min vs. 42.53 min; 11.53 % vs. 11.11 %; 88.46 % vs. 86.11 %; 11.53 % % vs. 13.88 %; respectively, and all P > 0.05).</div></div><div><h3>Conclusions</h3><div>Robotic navigation-assisted radiofrequency ablation of lung tumors is a feasible and safe technique. It can minimize needle adjustments, thereby shortening puncture time and reducing radiation exposure for patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"195 ","pages":"Article 112655"},"PeriodicalIF":3.3,"publicationDate":"2026-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0