P. Yu. Shkorbatova, A. A. Veshchitskii, A. A. Mikhalkin, N. I. Nikitina, A. V. Belyaev, N. S. Merkulyeva
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引用次数: 0
Abstract
The Cairo spiny mouse (Acomys cahirinus)
is a unique animal model for studying ontogenesis and regeneration.
Meanwhile, some peculiarities of its biology, specifically, low
fecundity and hence the small litter size, significantly complicate
experimental research. This work was aimed to study A. cahirinus behavior and reproduction
and to create a breeding colony in laboratory conditions. Here, we
describe the specific features of A. cahirinus colony
maintenance and management, including some handling and experimental
techniques, methods of nutritional and housing optimization, as
well as of animal marking for individual identification. Some reproductive
indices of A. cahirinus colony
are also provided. We modified the animal diet by supplementing
it with dried arthropods, an important component of the A. cahirinus natural diet, and created
environmental enrichment conditions by placing running wheels, tunnels
and huts into each cage. Our efforts yielded more than a 50% increase
in A. cahirinus population
over 9 months and a 98% overall survival rate of its offspring.
期刊介绍:
Journal of Evolutionary Biochemistry and Physiology publishes original experimental and theoretical and review articles related to evolution of the main forms of metabolism in connection with life origin; comparative and ontogenetic physiology and biochemistry, biochemical evolution of animal world; as well as evolution of functions; morphology, pharmacology, pathophysiology and ecological physiology. The journal welcomes manuscripts from all countries in the English or Russian language.