Breeding of the Cairo Spiny Mouse (Acomys cahirinus) in Laboratory Conditions

IF 0.6 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Evolutionary Biochemistry and Physiology Pub Date : 2024-08-29 DOI:10.1134/s0022093024040082
P. Yu. Shkorbatova, A. A. Veshchitskii, A. A. Mikhalkin, N. I. Nikitina, A. V. Belyaev, N. S. Merkulyeva
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Abstract

The Cairo spiny mouse (Acomys cahirinus) is a unique animal model for studying ontogenesis and regeneration. Meanwhile, some peculiarities of its biology, specifically, low fecundity and hence the small litter size, significantly complicate experimental research. This work was aimed to study A. cahirinus behavior and reproduction and to create a breeding colony in laboratory conditions. Here, we describe the specific features of A. cahirinus colony maintenance and management, including some handling and experimental techniques, methods of nutritional and housing optimization, as well as of animal marking for individual identification. Some reproductive indices of A. cahirinus colony are also provided. We modified the animal diet by supplementing it with dried arthropods, an important component of the A. cahirinus natural diet, and created environmental enrichment conditions by placing running wheels, tunnels and huts into each cage. Our efforts yielded more than a 50% increase in A. cahirinus population over 9 months and a 98% overall survival rate of its offspring.

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开罗刺鼠(Acomys cahirinus)在实验室条件下的繁殖
摘要开罗刺鼠(Acomys cahirinus)是一种独特的研究个体发育和再生的动物模型。这项工作的目的是研究A. cahirinus的行为和繁殖,并在实验室条件下建立一个繁殖群。在此,我们描述了A. cahirinus种群维护和管理的具体特点,包括一些处理和实验技术、营养和饲养优化方法,以及用于识别个体的动物标记。此外,还提供了 A. cahirinus 群落的一些繁殖指标。我们通过添加节肢动物干(A. cahirinus 天然食物的重要组成部分)来改善动物的饮食,并通过在每个笼子中放置跑轮、隧道和小屋来创造丰富的环境条件。通过我们的努力,在 9 个月的时间里,A. cahirinus 的数量增加了 50%以上,其后代的总体存活率达到 98%。
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来源期刊
自引率
33.30%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Journal of Evolutionary Biochemistry and Physiology  publishes original experimental and theoretical and review articles related to evolution of the main forms of metabolism in connection with life origin; comparative and ontogenetic physiology and biochemistry, biochemical evolution of animal world; as well as evolution of functions; morphology, pharmacology, pathophysiology and ecological physiology. The journal welcomes manuscripts from all countries in the English or Russian language.
期刊最新文献
Peculiarities of Brain Cell Functioning in Hyperglycemia and Diabetes Mellitus Tryptophan Signaling Molecules in Children with Different Developmental Dynamics of Obesity Comparative Skeletotopy of the Mammalian Lumbar Spinal Cord Breeding of the Cairo Spiny Mouse (Acomys cahirinus) in Laboratory Conditions A Comparative Analysis of Erythrocyte Osmotic Fragility across Vertebrate Taxa
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