A. V. Cherepanova, Yu. R. Bravy, A. V. Karabelsky, M. M. Kotova, A. S. Shcherbakova, K. V. Apukhtin, V. S. Nikitin, M. Yu. Bobrov, A. V. Kalueff
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引用次数: 0
Abstract
Neuroglia performs multiple important physiological functions,
including maintenance of brain homeostasis and metabolism, neuroprotection
and modulation of neurotransmission. Studying the role of neuroglia
is essential for understanding the pathogenesis of neurodegenerative
diseases, as well as nervous tissue repair in inflammation or traumatic
brain injuries, not infrequent in sports. However, it is difficult
to analyze the processes occurring in neuroglial cells because of
their high heterogeneity and no system of biomarkers allowing unambiguous
assessment of the nervous system’s functional state as a whole.
Here we analyze the data on clinically and biologically significant
molecular genetic markers of different types of neuroglia and discuss
the prospects for their use in sports physiology, including the functional
assessment of athletes with TBI of varying severity and other types
of sports-related traumas.
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