Liposomal Freight and Their Advanced Microstructure Characterization Techniques for Food and Nutraceutical Delivery

IF 2.6 Q2 FOOD SCIENCE & TECHNOLOGY ACS food science & technology Pub Date : 2024-08-28 DOI:10.1021/acsfoodscitech.4c00493
Punita Aggarwal, Sunil Kumar Sah, Velayutham Ravichandiran, Subhadeep Roy, Santanu Kaity
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Abstract

Liposome-based delivery technology has gained potential interest in the food sector because it is nontoxic, biocompatible, completely biodegradable, and nonimmunogenic. Numerous products have been researched to develop a safe, effective, and stable delivery system using liposomal technology. In this overview, we focus on different kinds of liposomal technology, how they are made, and how they are used to improve the safety and shelf life of foods and supplements. We also highlight several cutting-edge microstructure characterization methods that can be used to study liposomal micro- or nanodelivery systems in the food and nutraceutical industries. The regulatory approval process varies from country to country and market to market; therefore, finding the most appropriate, reliable, fast, and accurate characterization method is essential. Liposomes have low production cost, lack toxicity, and have innate versatility, representing promising new avenues for delivering food and nutraceuticals. Innovative methods are needed to characterize and standardize such food delivery systems because of the possibility of novel risks. Familiarity with the most recent developments in the characterization of liposomes could prove helpful. Moreover, these methods are not only limited to the characterization of liposomes but can also be used to describe other micro- or nanobased food and nutraceutical delivery systems.

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用于食品和营养品输送的脂质体货运及其先进的微结构表征技术
脂质体给药技术因其无毒、生物相容性好、可完全生物降解、无免疫原性等特点,在食品领域获得了潜在的关注。为了利用脂质体技术开发出安全、有效、稳定的给药系统,人们已经研究了大量产品。在本综述中,我们将重点介绍不同种类的脂质体技术、它们是如何制成的,以及它们是如何用于提高食品和保健品的安全性和保质期的。我们还重点介绍了几种前沿的微结构表征方法,这些方法可用于研究食品和保健品行业中的脂质体微量或纳米给药系统。不同国家和市场的监管审批程序各不相同;因此,找到最合适、可靠、快速和准确的表征方法至关重要。脂质体的生产成本低、无毒性,而且具有与生俱来的多功能性,是输送食品和营养保健品的大有可为的新途径。由于可能存在新的风险,因此需要创新的方法来表征和标准化此类食品输送系统。熟悉脂质体表征方面的最新进展可能会有所帮助。此外,这些方法不仅限于表征脂质体,还可用于描述其他微基或纳米基食品和营养保健品输送系统。
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