Evaluation of patient-specific quality assurance for fractionated stereotactic treatment plans with 6 and 10MV photon beams in beam-matched linacs.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiological Physics and Technology Pub Date : 2024-10-04 DOI:10.1007/s12194-024-00848-0
Mageshraja Kannan, Sathiyan Saminathan, Varatharaj Chandraraj, B Shwetha, D Gowtham Raj, K M Ganesh
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Abstract

Beam-matched linear accelerators (LA's) require accurate and precise dosimetry for fractionated stereotactic treatment. In this study, the beam data were validated by comparing the three-beam-matched LA's measured data and the vendor reference data. Upon its validation, the accuracy of the volumetric dose delivery for eighty patient-specific fractionated stereotactic treatment plans was evaluated. Measurements of the percentage depth dose (PDD), beam profiles, output factors (OFs), absolute output, and dynamic multi-leaf collimator (MLC) transmission factors for 6 MV and 10 MV flattening filter (FF) and flattening filter-free (FFF) photon beams were obtained from three-beam-matched LA's. The patient-specific quality assurance evaluation for all eighty plans was performed using PTW Octavius 1000 SRS™ array detectors for two-dimensional (2D) fluence measurement. The following 2D gamma passing criteria were used: 1%/1 mm, 2%/1 mm, 1%/2 mm, 2%/2 mm and 3%/2 mm. In all three LA's, gamma analysis for PDD and profile were above 97% with gamma criteria of 1%/1 mm. The differences OFs, absolute output, and dynamic MLC transmission factors were less than ± 1% of base value. For all eighty cases, the median passing rates on the three LA's were above 76%, 88%, 92%, 96%, and 98% for the above-mentioned gamma criteria of the three LA's. The beam-matched LA's showed good agreement between the measured and treatment planning system (TPS) calculated values for fractionated stereotactic VMAT plans with 6 MV and 10 MV (FF and FFF) photon beams. Patients can be shifted and treated on any beam-matched linac without the need of re-planning.

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评估在光束匹配直列加速器中使用6MV和10MV光子束的分层立体定向治疗计划的患者特定质量保证。
光束匹配直线加速器(LA)需要准确和精确的剂量测定来进行分层立体定向治疗。在这项研究中,通过比较三光束匹配 LA 的测量数据和供应商的参考数据,对光束数据进行了验证。经过验证后,对 80 个特定患者的分次立体定向治疗计划的容积剂量输送准确性进行了评估。从三个光束匹配的 LA 获得了 6 MV 和 10 MV 扁平化滤波器(FF)和无扁平化滤波器(FFF)光子束的百分比深度剂量(PDD)、光束轮廓、输出因子(OFs)、绝对输出和动态多叶准直器(MLC)传输因子的测量数据。使用PTW Octavius 1000 SRS™阵列探测器进行二维(2D)通量测量,对所有80个计划进行患者特定质量保证评估。二维伽马通过标准如下:1%/1毫米、2%/1毫米、1%/2毫米、2%/2毫米和3%/2毫米。在所有三个 LA 中,采用 1%/1毫米的伽玛标准,PDD 和剖面的伽玛分析结果都超过了 97%。OFs、绝对输出和动态 MLC 传输因子的差异均小于基准值的 ± 1%。在所有 80 个案例中,三种 LA 在上述伽马标准下的合格率中位数分别高于 76%、88%、92%、96% 和 98%。在使用 6 MV 和 10 MV(FF 和 FFF)光子束的分层立体定向 VMAT 计划中,光束匹配 LA 的测量值与治疗计划系统(TPS)的计算值之间显示出良好的一致性。病人可以在任何光束匹配的直列加速器上进行转移和治疗,而无需重新规划。
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来源期刊
Radiological Physics and Technology
Radiological Physics and Technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
12.50%
发文量
40
期刊介绍: The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
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