{"title":"Chemical enhancements and advanced manufacturing methods of Poly(Lactic acid) for tissue engineering applications","authors":"","doi":"10.1016/j.polymer.2024.127691","DOIUrl":null,"url":null,"abstract":"<div><div>Poly(lactic acid) (PLA) is a highly versatile biobased polymer with significant promise as a 3D-printable material for tissue engineering applications. PLA is sustainably produced at low cost, and exhibits properties such as biodegradability, biocompatibility, appreciable mechanical properties, and its potential for modification by a multitude of different additives and processing methods. This work provides an overview of recent research on the advanced manufacturing of PLA for tissue engineering applications. It also covers the most widely used additives and surface modifications to PLA, the effects of different processing methods, and the current shortcomings and future directions in this field.</div></div>","PeriodicalId":405,"journal":{"name":"Polymer","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0032386124010279","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
Poly(lactic acid) (PLA) is a highly versatile biobased polymer with significant promise as a 3D-printable material for tissue engineering applications. PLA is sustainably produced at low cost, and exhibits properties such as biodegradability, biocompatibility, appreciable mechanical properties, and its potential for modification by a multitude of different additives and processing methods. This work provides an overview of recent research on the advanced manufacturing of PLA for tissue engineering applications. It also covers the most widely used additives and surface modifications to PLA, the effects of different processing methods, and the current shortcomings and future directions in this field.
期刊介绍：
Polymer is an interdisciplinary journal dedicated to publishing innovative and significant advances in Polymer Physics, Chemistry and Technology. We welcome submissions on polymer hybrids, nanocomposites, characterisation and self-assembly. Polymer also publishes work on the technological application of polymers in energy and optoelectronics.
The main scope is covered but not limited to the following core areas:
Polymer Materials
Nanocomposites and hybrid nanomaterials
Polymer blends, films, fibres, networks and porous materials
Physical Characterization
Characterisation, modelling and simulation* of molecular and materials properties in bulk, solution, and thin films
Polymer Engineering
Advanced multiscale processing methods
Polymer Synthesis, Modification and Self-assembly
Including designer polymer architectures, mechanisms and kinetics, and supramolecular polymerization
Technological Applications
Polymers for energy generation and storage
Polymer membranes for separation technology
Polymers for opto- and microelectronics.
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