Prevalence, incidence, impairment, course, and diagnostic progression and transition of eating disorders, overweight, and obesity in a large prospective study of high-risk young women.

IF 3.1 Q2 PSYCHIATRY Journal of psychopathology and clinical science Pub Date : 2024-11-07 DOI:10.1037/abn0000965
Eric Stice, Chris Desjardins, Heather Shaw, Sarah Siegel, Kristen Gee, Paul Rohde
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Abstract

We examined prevalence, incidence, impairment, course, and diagnostic transitions for Diagnostic and Statistical Manual of Mental Disorders, fifth edition, eating disorders, overweight, and obesity in a high-risk sample of 1,952 young women (Mage = 19.7 years) who completed diagnostic interviews over a 3-year period. The baseline prevalence of any eating disorder was 13.3% and 25.4% showed onset (incidence) over 3-year follow-up. Baseline prevalence of overweight and obesity were 17.2% and 11.9%, respectively, with respective 3-year incidence rates of 18.3% and 6.8%. The average duration of eating disorders ranged from 2.2 to 5.0 months. Episode duration for overweight and obesity were 14.9 and 20.0 months, respectively. Most eating disorders (82%-96%) showed remission within 1 year; recurrence rates varied from 12% (atypical anorexia nervosa [AN]) to 44% (subthreshold bulimia nervosa). Three-year remission rates for overweight (53%) and obesity (34%) were lower, as was recurrence (15% and 9%, respectively). All eating disorders were characterized by a mixture of binge eating and compensatory weight control behaviors. Functional impairment was elevated for half the examined eating disorders and obesity. Diagnostic progression varied from 3% of those with atypical AN progressing to AN to 29% of those with subthreshold binge eating disorder progressing to binge eating disorder. Regarding diagnostic crossover, the most frequent pattern was shifting from a threshold to a subthreshold eating disorder, followed by shifting from a binge-related eating disorder to overweight. Results extend knowledge of the natural history of eating disorders and provide novel evidence of the relation between eating disorders and overweight/obesity. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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在一项针对高危年轻女性的大型前瞻性研究中,饮食失调、超重和肥胖症的流行率、发病率、损伤、病程以及诊断进展和转变。
我们对 1952 名年轻女性(平均年龄 = 19.7 岁)的高风险样本进行了研究,这些样本在 3 年内完成了诊断访谈,研究了《精神障碍诊断与统计手册》(第五版)、进食障碍、超重和肥胖的患病率、发病率、损伤、病程和诊断转换。任何饮食失调症的基线患病率为 13.3%,25.4% 的患者在 3 年的随访中发病(发病率)。超重和肥胖的基线发病率分别为 17.2% 和 11.9%,3 年的发病率分别为 18.3% 和 6.8%。饮食失调的平均持续时间从 2.2 个月到 5.0 个月不等。超重和肥胖的发病时间分别为 14.9 个月和 20.0 个月。大多数饮食失调症(82%-96%)在一年内得到缓解;复发率从12%(非典型神经性厌食症[AN])到44%(亚阈值神经性贪食症)不等。超重(53%)和肥胖(34%)的三年缓解率较低,复发率也较低(分别为 15%和 9%)。所有饮食失调症的特点都是暴饮暴食和补偿性体重控制行为并存。在接受检查的饮食失调症和肥胖症患者中,有一半人的功能障碍程度较高。诊断进展各不相同,从3%的非典型自闭症患者进展为自闭症,到29%的阈下暴食症患者进展为暴食症。在诊断交叉方面,最常见的模式是从阈值进食障碍转变为亚阈值进食障碍,其次是从暴饮暴食相关进食障碍转变为超重。研究结果拓展了人们对饮食失调自然史的认识,并为饮食失调与超重/肥胖之间的关系提供了新的证据。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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Modeling the dynamics of addiction relapse via the double-well potential system. Adolescent social anxiety is associated with diminished discrimination of anticipated threat and safety in the bed nucleus of the stria terminalis. Prevalence, incidence, impairment, course, and diagnostic progression and transition of eating disorders, overweight, and obesity in a large prospective study of high-risk young women. Reification of the p factor draws attention away from external causes of psychopathology. Clarifying the place of p300 in the empirical structure of psychopathology over development.
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