{"title":"Targeted review of the maximum residue levels (MRLs) for dimethomorph","authors":"European Food Safety Authority (EFSA)","doi":"10.2903/j.efsa.2024.9093","DOIUrl":null,"url":null,"abstract":"<p>In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a targeted risk assessment for dimethomorph considering the residue definition and the toxicological reference values (TRVs) derived during the renewal of the approval of dimethomorph and the most recent version of the EFSA Pesticide Residues Intake Model (PRIMo) (rev.3.1). EFSA confirmed that the current TRVs are sufficiently protective for consumers, including the identified hazard indicative of endocrine disruption. Furthermore, EFSA identified all the codex maximum residue limits (CXLs) and import tolerances that are covered by existing maximum residue levels (MRLs) and performed chronic and acute dietary risk assessment to support risk managers during the decision-making. A screening of all existing MRLs was also performed. The exposure calculations performed by EFSA showed that the existing MRLs, including the ones based on CXLs or import tolerances, do not lead to consumers intake concerns.</p>","PeriodicalId":11657,"journal":{"name":"EFSA Journal","volume":"22 11","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2024.9093","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"EFSA Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2024.9093","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a targeted risk assessment for dimethomorph considering the residue definition and the toxicological reference values (TRVs) derived during the renewal of the approval of dimethomorph and the most recent version of the EFSA Pesticide Residues Intake Model (PRIMo) (rev.3.1). EFSA confirmed that the current TRVs are sufficiently protective for consumers, including the identified hazard indicative of endocrine disruption. Furthermore, EFSA identified all the codex maximum residue limits (CXLs) and import tolerances that are covered by existing maximum residue levels (MRLs) and performed chronic and acute dietary risk assessment to support risk managers during the decision-making. A screening of all existing MRLs was also performed. The exposure calculations performed by EFSA showed that the existing MRLs, including the ones based on CXLs or import tolerances, do not lead to consumers intake concerns.
根据(EC) No 396/2005法规第43条,欧盟委员会要求欧洲食品安全局对二甲吗啉进行一次有针对性的风险评估,评估时应考虑二甲吗啉的残留定义、更新批准过程中得出的毒理学参考值(TRVs)以及欧洲食品安全局农药残留摄入量模型(PRIMo)的最新版本(rev.3.1)。欧洲食品安全局确认,目前的 TRV 值足以保护消费者,包括已确定的内分泌干扰危害。此外,欧洲食物安全局还确定了现有最高残留限量(MRL)所涵盖的所有法典最高残留限量(CXL)和进口容许量,并进行了慢性和急性膳食风险评估,以在决策过程中为风险管理人员提供支持。此外,还对所有现有最高残留限量进行了筛查。欧洲食物安全局进行的暴露计算表明,现有的最高残留限量,包括基于CXL或进口耐受量的最高残留限量,不会导致消费者对摄入量的担忧。
期刊介绍:
The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.