Correction to “A Double Network Composite Hydrogel with Self-Regulating Cu2+/Luteolin Release and Mechanical Modulation for Enhanced Wound Healing”

IF 16 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY ACS Nano Pub Date : 2024-12-03 DOI:10.1021/acsnano.4c14461
Yue Li, Yunpeng Wang, Yuanyuan Ding, Xi Fan, Liansong Ye, Qingqing Pan, Bowen Zhang, Peng Li, Kui Luo, Bing Hu, Bin He, Yuji Pu
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Abstract

In Figure 2d, the SEM of the GSC10 was incorrectly used. We have replaced it with the correct image and recalculated the pore size distributions. Figure 2. Characterization of blank GS and GSC hydrogels. (a–c) Rheological properties of (a) GS0.8% with time after UV irradiation; (b) GS hydrogels prepared with different SA concentrations at ω = 10 rad/s; GSC hydrogels prepared with various Cu2+ concentrations at ω = 10 rad/s. (d) SEM images and pore size distributions of GSC hydrogels. In Figure 6a, there was a typo in the group label. The group name “GC/PBE@Lut” should have been “GS/PBE@Lut.” We have corrected the figure accordingly. Figure 6. In vitro wound healing and angiogenesis. (a) Scratch assay assessing the proliferation and migration abilities of HUVEC after coculturing with different materials. (b) Quantification of wound closure ratios in the scratch assay. (c) Images of tube formation by HUVECs after coincubation with hydrogel extracts for 6 h. Quantifications of nodes (d) and tube length (e) in the tube formation assay. (f) RT-qPCR analysis of VEGF expression in HUVECs. *p < 0.05, **p < 0.01, and ***p < 0.001. Similarly, in the results and discussion sections 2.4, 2.5, and 2.7, GC/PBE@Lut should be changed into GS/PBE@Lut. The revised text is as follows: In Section 2.4: “The antibacterial efficacies of GSC, GS/PBE@Lut, and GSC/PBE@Lut against Escherichia coli and Staphylococcus aureus were investigated using a coculture method (Figure 4d).” In section 2.5: “To examine the effect of GS/PBE@Lut and GSC/PBE@Lut on cell proliferation and migration in chronic wound environments, a scratch assay was conducted under conditions of pH 7.4 and high oxidative stress induced by exogenous 100 μM H2O2.” “The results indicated a substantial enhancement in cell proliferation and migration for GSC, GS/PBE@Lut, and GSC/PBE@Lut compared with the H2O2 group (Figure 6a).” “Promoting vascular regeneration is paramount to tissue regeneration. Following a 6 h coculture of HUVECs with extracts from the control group, GSC, GS/PBE@Lut, and GSC/PBE@Lut, the number of nodes and tube lengths were measured (Figure 6c). ” In Section 2.7: “The fluorescence intensities of GS/PBE@Lut and GSC/PBE@Lut were notably lower than those of the control group (Figure 9b,d).” “Quantitative analysis of CD206+/CD68+ cell percentages indicated 2.95- and 0.94-fold increases in M2 polarization for GSC/PBE@Lut and GS/PBE@Lut treatments, respectively (Figure 9e).” “Quantitative analysis of iNOS+/CD68+ cell percentages revealed no M1 macrophages in the GSC/PBE@Lut and GS/PBE@Lut groups, while the control and GSC groups exhibited M1 macrophages (Figure 9f).” In Figure 8, the skin section image of the GS group on day 15 was incorrectly used. We have replaced it with the correct image. Figure 8. (a) H&E staining of the wound tissue of days 5, 10, and 15; scale bar 100 μm. (b) Masson staining of the wound tissue; scale bar 1000 μm. Quantifications of collagen content (c) and epidermal thickness (d). *p < 0.05 and **p < 0.01. These are unintentional errors and do not affect the scientific conclusions corresponding to the main text of the article. All coauthors have approved this correction. We express our profound apologies for the inconvenience caused by our negligence to the editor and readers. This article has not yet been cited by other publications.

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对“具有自我调节Cu2+/木犀草素释放和机械调节促进伤口愈合的双网络复合水凝胶”的更正
在图2d中,错误地使用了GSC10的SEM。我们将其替换为正确的图像,并重新计算孔径分布。图2。空白GS和GSC水凝胶的表征。(a - c) (a) GS0.8%紫外辐照后随时间的流变性能;(b) ω = 10 rad/s下不同SA浓度制备的GS水凝胶;在ω = 10 rad/s下制备不同Cu2+浓度的GSC水凝胶。(d) GSC水凝胶的SEM图像和孔径分布。在图6a中,组标签中有一个错别字。组名“GC/PBE@Lut”应该是“GS/PBE@Lut”。我们已经对这个数字做了相应的修正。图6。体外伤口愈合和血管生成。(a)刮擦法评估不同材料共培养后HUVEC的增殖和迁移能力。(b)划痕实验中伤口闭合率的量化。(c) HUVECs与水凝胶提取物共孵育6小时后的成管图像。成管实验中节点(d)和管长(e)的定量。(f) huvec中VEGF表达的RT-qPCR分析。* p & lt;0.05, **p <;0.01, ***p <;0.001. 类似地,在结果和讨论节2.4、2.5和2.7中,GC/PBE@Lut应该改为GS/PBE@Lut。修改后的文本如下:在2.4节中:“使用共培养方法研究了GSC、GS/PBE@Lut和GSC/PBE@Lut对大肠杆菌和金黄色葡萄球菌的抗菌效果(图4d)。”章节2.5:“为了研究GS/PBE@Lut和GSC/PBE@Lut对慢性伤口环境中细胞增殖和迁移的影响,我们在pH 7.4和外源100 μM H2O2诱导的高氧化应激条件下进行了划痕实验。结果表明,与H2O2组相比,GSC、GS/PBE@Lut和GSC/PBE@Lut的细胞增殖和迁移明显增强(图6a)。”“促进血管再生对组织再生至关重要。HUVECs与对照组、GSC、GS/PBE@Lut和GSC/PBE@Lut的提取物共培养6小时后,测量节点数量和管长(图6c)。在2.7节中,GS/PBE@Lut和GSC/PBE@Lut的荧光强度明显低于对照组(图9b、d)。CD206+/CD68+细胞百分比的定量分析表明,GSC/PBE@Lut和GS/PBE@Lut处理的M2极化分别增加了2.95倍和0.94倍(图9e)。“定量分析iNOS+/CD68+细胞百分比显示,GSC/PBE@Lut和GS/PBE@Lut组中没有M1巨噬细胞,而对照组和GSC组显示M1巨噬细胞(图9f)。”图8中,GS组第15天的皮肤切片图像使用错误。我们已经用正确的图像替换了它。图8。(a)第5、10、15天创面组织H&;E染色;标尺100 μm。(b)伤口组织马松染色;比例尺1000 μm。胶原含量(c)和表皮厚度(d)的定量测定。*p &;0.05和**p <;0.01. 这些都是无意的错误,并不影响与文章正文相对应的科学结论。所有合著者都同意这一更正。由于我们的疏忽给编辑和读者带来的不便,我们深表歉意。这篇文章尚未被其他出版物引用。
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来源期刊
ACS Nano
ACS Nano 工程技术-材料科学:综合
CiteScore
26.00
自引率
4.10%
发文量
1627
审稿时长
1.7 months
期刊介绍: ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.
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